Evidence map›Paper›PMID 34983100›Full record

ArticleKorean journal of radiology2022

Bone Suppression on Chest Radiographs for Pulmonary Nodule Detection: Comparison between a Generative Adversarial Network and Dual-Energy Subtraction.

Kyungsoo Bae, Dong Yul Oh, Il Dong Yun, Kyung Nyeo Jeon

Open access · greenAbstract read
In one paragraph

Article in Korean journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. GAN-based bone suppression using a combined loss function.Frontiers in artificial intelligence · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kyungsoo BaeDepartment of Radiology, Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.ORCID 0000-0002-2545-2682
Dong Yul OhMonitor Corporation, Seoul, Korea.ORCID 0000-0002-8393-7960
Il Dong YunDivision of Computer and Electronic System Engineering, Hankuk University of Foreign Studies, Yongin, Korea.ORCID 0000-0001-9893-8897
Kyung Nyeo JeonDepartment of Radiology, Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.ORCID 0000-0003-2267-0366
Changwon National University · KRHankuk University of Foreign Studies · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the effects of bone suppression imaging using deep learning (BSp-DL) based on a generative adversarial network (GAN) and bone subtraction imaging using a dual energy technique (BSt-DE) on radiologists' performance for pulmonary nodule detection on chest radiographs (CXRs). MATERIALS AND

methodsA total of 111 adults, including 49 patients with 83 pulmonary nodules, who underwent both CXR using the dual energy technique and chest CT, were enrolled. Using CT as a reference, two independent radiologists evaluated CXR images for the presence or absence of pulmonary nodules in three reading sessions (standard CXR, BSt-DE CXR, and BSp-DL CXR). Person-wise and nodule-wise performances were assessed using receiver-operating characteristic (ROC) and alternative free-response ROC (AFROC) curve analyses, respectively. Subgroup analyses based on nodule size, location, and the presence of overlapping bones were performed.

resultsBSt-DE with an area under the AFROC curve (AUAFROC) of 0.996 and 0.976 for readers 1 and 2, respectively, and BSp-DL with AUAFROC of 0.981 and 0.958, respectively, showed better nodule-wise performance than standard CXR (AUAFROC of 0.907 and 0.808, respectively;

conclusionBSp-DL (GAN-based bone suppression) showed comparable performance to BSt-DE and can improve radiologists' performance in detecting pulmonary nodules on CXRs. Nevertheless, for better delineation of small and peripheral nodules, further technical improvements are required.

Indexed as

Lung NeoplasmsMultiple Pulmonary NodulesSolitary Pulmonary NoduleAdultHumansRadiography, ThoracicROC CurveSensitivity and SpecificityBone suppression imagingChest radiographyDeep learningGenerative adversarial networkPulmonary nodules

Identifiers

PMID34983100
PMCPMC8743147
OpenAlexW4205872908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.