Evidence map›Paper›PMID 34983098›Full record

ArticleKorean journal of radiology2022

Relationship between

Lihong Bu, Ning Tu, Ke Wang, Ying Zhou, Xinli Xie, Xingmin Han, Huiqin Lin, Hongyan Feng

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Nonlinear association between standardized uptake value (SUV) index based onQuantitative imaging in medicine and surgery · 2026
    Article
  4. Observational
  5. BMC medical imaging · 2025
    Article
  6. AssessingNuclear medicine and molecular imaging · 2025
    Article
  7. Journal of clinical medicine · 2024
    Article
  8. Article
  9. Imaging phenotyping usingInsights into imaging · 2024
    Article
  10. New Oncologic Imaging Section in theKorean journal of radiology · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. The Role and Potential ofDiagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Lihong BuPET/CT/MRI and Molecular Imaging Center, Renmin Hospital of Wuhan University, Wuhan, China.ORCID 0000-0002-1102-3158
Ning TuPET/CT/MRI and Molecular Imaging Center, Renmin Hospital of Wuhan University, Wuhan, China.ORCID 0000-0002-8845-9689
Ke WangPET/CT/MRI and Molecular Imaging Center, Renmin Hospital of Wuhan University, Wuhan, China.ORCID 0000-0003-0379-876X
Ying ZhouPET/CT/MRI and Molecular Imaging Center, Renmin Hospital of Wuhan University, Wuhan, China.ORCID 0000-0003-0408-3731
Xinli XieDepartment of Nuclear Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0003-1487-7527
Xingmin HanDepartment of Nuclear Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0002-4069-6095
Huiqin LinDepartment of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, China.ORCID 0000-0003-1340-6109
Hongyan FengPET/CT/MRI and Molecular Imaging Center, Renmin Hospital of Wuhan University, Wuhan, China. fenghongyan870625@163.com.ORCID 0000-0003-1352-3196
Wuhan University · CNFirst Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship between MATERIALS AND

methodsThis retrospective study included 419 patients (150 males, 269 females; median age, 59.0 years; age range, 23.0-84.0 years) who had undergone surgical removal of stage IA-IIIA lung adenocarcinoma and had preoperative PET/CT data of lung tumors. The maximum standardized uptake values (SUVmax), background-subtracted volume (BSV), and background-subtracted lesion activity (BSL) derived from PET/CT were measured. The IASLC/ATS/ERS subtypes, Ki67 score, and epidermal growth factor/anaplastic lymphoma kinase (EGFR/ALK) mutation status were evaluated. The PET/CT semi-quantitative parameters were compared between the tumor subtypes using the Mann-Whitney U test or the Kruskal-Wallis test. The optimum cutoff values of the PET/CT semi-quantitative parameters for distinguishing the IASLC/ATS/ERS subtypes were calculated using receiver operating characteristic curve analysis. The correlation between the PET/CT semi-quantitative parameters and pathological parameters was analyzed using Spearman's correlation. Statistical significance was set at

resultsSUVmax, BSV, and BSL values were significantly higher in invasive adenocarcinoma (IA) than in minimally IA (MIA), and the values were higher in MIA than in adenocarcinoma in situ (AIS) (all

conclusionAs noninvasive surrogates, preoperative PET/CT semi-quantitative parameters could imply IASLC/ATS/ERS subtypes and Ki67 index and thus may contribute to improved management of precise surgery and postoperative adjuvant therapy.

Indexed as

Adenocarcinoma of LungLung NeoplasmsAdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedNeoplasm StagingPositron Emission Tomography Computed TomographyPrognosisRetrospective StudiesYoung AdultFluorodeoxyglucose F18Background-subtracted lesion activity (BSL)Background-subtracted volume (BSV)IASLC/ETS/ERS classificationLung adenocarcinomaMaximum standardized uptake value (SUVmax)

Identifiers

PMID34983098
PMCPMC8743143
OpenAlexW4206593348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.