Evidence map›Paper›PMID 34983087›Full record

ReviewThe world journal of men's health2022

Multidisciplinary Consensus on the Prevention and Treatment of Osteoporosis and Fragility Fractures in Patients with Prostate Cancer Receiving Androgen-Deprivation Therapy.

Enrique Casado, Angel Borque-Fernando, Manuel Caamaño, Jenaro Graña, Jesús Muñoz-Rodríguez, Juan Morote

Open access · diamondAbstract readReview
In one paragraph

Review in The world journal of men's health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Disproportionality analysis of adverse events associated with degarelix: a real-world study from the FDA Adverse Event Reporting System (FAERS) database.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Association between BMD and coronary artery calcification: an observational and Mendelian randomization study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Observational
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Enrique CasadoDepartment of Rheumatology, University Hospital Parc Taulí, I3PT Research Institute (UAB), Sabadell, Barcelona, Spain. quique.casado@gmail.com.ORCID https://orcid.org/0000-0001-8839-6430
Angel Borque-FernandoDepartment of Urology, University Hospital Miguel Servet, Instituto de Investigación Sanitaria-Aragón, Zaragoza, Spain.ORCID https://orcid.org/0000-0003-0178-4567
Manuel CaamañoDepartment of Rheumatology, University Clinical Hospital of Santiago de Compostela, A Coruña, Spain.ORCID https://orcid.org/0000-0003-4436-9507
Jenaro GrañaDepartment of Rheumatology, A Coruña University Clinical Hospital, A Coruña, Spain.ORCID https://orcid.org/0000-0001-9041-8117
Jesús Muñoz-RodríguezDepartment of Urology, University Hospital Parc Taulí, Sabadell, Barcelona, Spain.ORCID https://orcid.org/0000-0001-5406-4729
Juan MoroteDepartment of Urology, Vall d'Hebron Hospital, Barcelona, Spain.ORCID https://orcid.org/0000-0002-2168-323X
Universidade da Coruña · ESHospital de Sabadell · ESInstituto de Investigación Sanitaria Aragón · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with prostate cancer (PCa) on androgen-deprivation therapy (ADT) are at high risk of osteoporosis and fragility fractures. We aimed to provide some practical insights into the delivery of optimal bone health care for PCa patients, particularly those on ADT. An interdisciplinary group of experts, including urologists and rheumatologists developed recommendations based on their expertise, current evidence and guidelines. The multidisciplinary group's main recommendations are: fragility fracture risk should be assessed in all PCa patient, especially, in those under ADT. FRAX® tool may be incorporated into clinical practice to identify patients at high risk of fracture. Bone mineral density (BMD) should be measured routinely by dual energy X-ray absorptiometry in all patients scheduled for or on ADT. Thoracic and lumbar spine X-ray may be performed at the initial evaluation of patients with the diagnosis of osteoporosis and in case of suspected clinical vertebral fracture. Basic laboratory tests are recommended to exclude secondary osteoporosis. Treatment with bisphosphonates or denosumab should be considered in patients on ADT with fragility fracture, osteoporosis (BMD T-score ≤-2.5), or high risk of fracture according to FRAX®. Referral to a bone metabolism specialist should be contemplated in some cases. The recommendations provided in this document, tailored for clinicians treating PCa patients, may be of help to identify and treat patients at high risk of fracture.

Indexed as

Androgen antagonistsDenosumabDiphosphonatesOsteoporosisProstatic neoplasms

Identifiers

PMID34983087
PMCPMC8761232
OpenAlexW4205557495

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.