Evidence map›Paper›PMID 34982508›Full record

ArticleJournal of cosmetic dermatology2022

Retrospective evaluation of patients with chronic spontaneous urticaria using omalizumab during the COVID-19 pandemic.

Sema Koç Yıldırım, Neslihan Demirel Öğüt, Ece Erbağcı

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Journal of cosmetic dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. The effect of COVID-19 on patients recieving omalizumab treatment.Revue francaise d'allergologie (2009) · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sema Koç YıldırımDepartment of Dermatology and Venereology, Uşak University Training and Research Hospital, Uşak, Turkey.ORCID https://orcid.org/0000-0002-0633-1770
Neslihan Demirel ÖğütDepartment of Dermatology and Venereology, Uşak University Training and Research Hospital, Uşak, Turkey.ORCID https://orcid.org/0000-0001-5051-5481
Ece ErbağcıDepartment of Dermatology and Venereology, Uşak University Training and Research Hospital, Uşak, Turkey.ORCID https://orcid.org/0000-0002-2887-0492
Usak University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOmalizumab (OMZ) is a monoclonal anti-immunoglobulin E antibody used in patients with chronic spontaneous urticaria (CSU). The data about using OMZ during the coronavirus disease 19 (COVID-19) pandemic are limited. The aim of this study was to evaluate the status of having COVID-19 and relationships between COVID-19, vaccination, and urticaria symptoms of CSU patients on OMZ.

methodWe conducted a retrospective cohort study of 36 adult CSU patients treated with OMZ. Demographic data, the results of COVID-19 real-time polymerase chain reaction (RT-PCR), and vaccination status were recorded from the electronic medical records.

resultsThirty-six patients, 23 women, and 13 men were evaluated. The mean age was 45.81 years. Two patients were diagnosed with COVID-19 while using OMZ. Four patients interrupted their OMZ treatment during the pandemic, and OMZ treatments were restarted in all patients. There were 28 patients who had at least one dose of vaccine (inactive and/or mRNA vaccine). Only one patient had an urticaria exacerbation after the first dose of mRNA vaccine.

conclusionAs a result, our findings have shown that omalizumab treatment in CSU patients during the COVID-19 pandemic does not increase the risk of COVID-19 infection and omalizumab can be used safely.

Indexed as

Anti-Allergic AgentsChronic UrticariaCOVID-19OmalizumabAdultChronic DiseaseCOVID-19 VaccinesFemaleHumansMaleMiddle AgedmRNA VaccinesPandemicsRetrospective StudiesTreatment OutcomeVaccines, SyntheticAnti-Allergic AgentsCOVID-19 VaccinesmRNA VaccinesOmalizumabVaccines, Syntheticchronic spontaneous urticariaCOVID-19omalizumabpandemic

Identifiers

PMID34982508
OpenAlexW4205677184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.