Evidence map›Paper›PMID 34982385›Full record

ArticleEnvironmental science and pollution research international2022

Assessment of disease burden in the arsenic exposed population of Chapar village of Samastipur district, Bihar, India, and related mitigation initiative.

Arun Kumar, Md Samiur Rahman, Mohammad Ali, Pascal Salaun, Arthur Gourain, Suresh Kumar, Ranjit Kumar, Pintoo Kumar Niraj, Mukesh Kumar, Dhruv Kumar and 6 more

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Article in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 3 countries.

Arun KumarMahavir Cancer Sansthan and Research Centre, Phulwarisharif, Patna, 801505, Bihar, India. drarunk31@gmail.com.ORCID http://orcid.org/0000-0002-8946-5909
Md Samiur RahmanMahavir Cancer Sansthan and Research Centre, Phulwarisharif, Patna, 801505, Bihar, India.
Mohammad AliMahavir Cancer Sansthan and Research Centre, Phulwarisharif, Patna, 801505, Bihar, India.
Pascal SalaunUniversity of Liverpool, Liverpool, UK.
Arthur GourainUniversity of Liverpool, Liverpool, UK.
Suresh KumarCentral Ground Water Board, Patna, Bihar, India.
Ranjit KumarCentral University of Himachal Pradesh, Kangra, HP, India.
Pintoo Kumar NirajMahavir Cancer Sansthan and Research Centre, Phulwarisharif, Patna, 801505, Bihar, India.
Mukesh KumarMahavir Cancer Sansthan and Research Centre, Phulwarisharif, Patna, 801505, Bihar, India.
Dhruv KumarAmity Institute of Molecular Medicine & Stem Cell Research (AIMMSCR), Amity University Uttar Pradesh, Noida, India.
Akhouri BishwapriyaGeological Survey of India, Patna, Bihar, India.
Shreya SinghGeological Survey of India, Patna, Bihar, India.
Krishna MurtiNational Institute of Pharmaceutical Education and Research (NIPER), Hajipur, Bihar, India.
Sameer DhingraNational Institute of Pharmaceutical Education and Research (NIPER), Hajipur, Bihar, India.
Maiko SakamotoThe University of Tokyo, Chiba, Japan.
Ashok Kumar GhoshMahavir Cancer Sansthan and Research Centre, Phulwarisharif, Patna, 801505, Bihar, India.
Mahavir Cancer Institute and Research Centre · INGeological Survey of India · INNational Institute of Pharmaceutical Education and Research · INUniversity of Liverpool · GBAmity University · INCentral Ground Water Board · INCentral University of Himachal Pradesh · INThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fast growing arsenic menace is causing serious health hazards in Bihar, India, with an estimated 10 million people at risk. The exposed population is often unaware of the problem, which only amplifies the burden of arsenic health effects. In the present study, we have assessed the current situation of arsenic exposure in Chapar village of Samastipur district, Bihar. The health of the inhabitants was assessed and correlated with (1) arsenic concentrations in the groundwater of individual wells and (2) arsenic concentration found in their hair and urine. Altogether, 113 inhabitants were assessed, and 113 hair, urine and groundwater samples were collected. The health study reveals that the exposure to arsenic has caused serious health hazard amongst the exposed population with pronounced skin manifestations, loss of appetite, anaemia, constipation, diarrhoea, general body weakness, raised blood pressure, breathlessness, diabetes, mental disabilities, diabetes, lumps in the body and few cancer incidences. It was found that 52% of the total collected groundwater samples had arsenic levels higher than the WHO limit of 10 µg/l (with a maximum arsenic concentration of 1212 µg/l) and the reduced arsenite was the predominant form in samples tested for speciation (N = 19). In the case of hair samples, 29% of the samples had arsenic concentrations higher than the permissible limit of 0.2 mg/kg, with a maximum arsenic concentration of 46 µg/l, while in 20% exposed population, there was significant arsenic contamination in urine samples > 50 µg/l. In Chapar village, the probability of carcinogenic-related risk in the exposed population consuming arsenic contaminated water is 100% for children, 99.1% for females and 97.3% for male subjects. The assessment report shared to the government enabled the village population to receive two arsenic filter units. These units are currently operational and catering 250 households providing arsenic-free water through piped water scheme. This study therefore identified a significant solution for this arsenic-exposed population.

Indexed as

ArsenicGroundwaterWater Pollutants, ChemicalChildCost of IllnessFemaleHumansIndiaMaleWaterArsenicWaterWater Pollutants, ChemicalArsenic exposureCancer riskChapar villageDisease burdenGangetic plainsHazard quotient (HQ)Health assessmentMitigation initiative

Identifiers

PMID34982385
OpenAlexW4205104522

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.