ArticleJournal of ophthalmic inflammation and infection2022
Ocular inflammatory events following COVID-19 vaccination: a multinational case series.
Article in Journal of ophthalmic inflammation and infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
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Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- A Systematic Review of Ocular Complications Following Different Types of Covid-19 Vaccines.Journal of immunology research · 2025Pooled it
- Ocular Complications after COVID-19 Vaccination: A Systematic Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Vaccine-Associated Anterior Uveitis.Vaccines · 2026Review
- A rare case of multisystem autoimmune disease presenting with retinopathy and alopecia post COVID-19 vaccination.Journal of ophthalmic inflammation and infection · 2026Article
- Acute zonal occult outer retinopathy (AZOOR) complex associated with torpedo retinopathy following COVID-19 recombinant mRNA vaccination: a case report of a rare clinical presentation.BMC ophthalmology · 2025Article
- Drug-Induced Uveitis: Patterns, Pathogenesis and Clinical Implications.Clinical optometry · 2025Review
- Ocular Lesions Related to COVID-19 and Its Vaccines.Journal of ophthalmology · 2025Review
- Infectious eye disease in the 21st century-an overview.Eye (London, England) · 2024Review
- Increased incidence and diverse manifestations of multiple evanescent white dot syndrome during the COVID-19 pandemic.Scientific reports · 2024Article
- Mimickers of anterior uveitis, scleritis and misdiagnoses- tips and tricks for the cornea specialist.Journal of ophthalmic inflammation and infection · 2024Review
- Posterior scleritis following COVID-19 vaccination or infection simulating uveal melanoma in 8 consecutive patients.Eye (London, England) · 2024Article
- Unilateral Anterior Scleritis Following the Booster Shot of Inactivated COVID-19 (Sinopharm) Vaccine in a 52-Year-Old Woman: A Case Report.Case reports in rheumatology · 2024Article
- Panuveitis and optic neuropathy following SARS-COV-2 in the absence of multisystem inflammatory syndrome in a child.American journal of ophthalmology case reports · 2023Article
- Ocular inflammatory events and COVID-19 vaccination: correspondence.Journal of ophthalmic inflammation and infection · 2023Article
- Ocular manifestations following COVID-19 vaccination.Journal of ophthalmic inflammation and infection · 2023Article
- Orbital inflammation following COVID-19 vaccination: A case series and literature review.International ophthalmology · 2023Review
- Challenges in posterior uveitis-tips and tricks for the retina specialist.Journal of ophthalmic inflammation and infection · 2023Review
- Intraocular inflammation following COVID-19 vaccination: the clinical presentations.International ophthalmology · 2023Article
- Single cell characteristics of patients with vaccine-related adverse reactions following inactivated COVID-19 vaccination.Human vaccines & immunotherapeutics · 2023Article
- A COVID-19 perspective of Vogt-Koyanagi-Harada disease.Indian journal of ophthalmology · 2023Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammatory adverse events following COVID-19 vaccination are being reported amidst the growing concerns regarding vaccine's immunogenicity and safety, especially in patients with pre-existing inflammatory conditions.
methodsMultinational case series of patients diagnosed with an ocular inflammatory event within 14 days following COVID-19 vaccination collected from 40 centres over a 3 month period in 2021.
resultsSeventy patients presented with ocular inflammatory events within 14 days following COVID-19 vaccination. The mean age was 51 years (range, 19-84 years). The most common events were anterior uveitis (n = 41, 58.6%), followed by posterior uveitis (n = 9, 12.9%) and scleritis (n = 7, 10.0%). The mean time to event was 5 days and 6 days (range, 1-14 days) after the first and second dose of vaccine, respectively. Among all patients, 36 (54.1%) had a previous history of ocular inflammatory event. Most patients (n = 48, 68.6%) were managed with topical corticosteroids. Final vision was not affected in 65 (92.9%), whereas 2 (2.9%) and 3 (4.3%) had reduction in visual acuity reduced by ≤3 lines and > 3 lines, respectively. Reported complications included nummular corneal lesions (n = 1, 1.4%), cystoid macular oedema (n = 2, 2.9%) and macular scarring (n = 2, 2.9%).
conclusionOcular inflammatory events may occur after COVID-19 vaccination. The findings are based on a temporal association that does not prove causality. Even in the possibility of a causal association, most of the events were mild and had a good visual outcome.
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