Evidence map›Paper›PMID 34982273›Full record

ReviewMedical oncology (Northwood, London, England)2022

Novel molecules as the emerging trends in cancer treatment: an update.

Priyanka Sekar, Raashmi Ravitchandirane, Sofia Khanam, Nethaji Muniraj, Ananda Vayaravel Cassinadane

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Priyanka SekarSri Venkateshwaraa Medical College Hospital and Research Centre, Pondicherry, 605102, India.ORCID http://orcid.org/0000-0003-1797-2669
Raashmi RavitchandiraneSri Venkateshwaraa Medical College Hospital and Research Centre, Pondicherry, 605102, India.ORCID http://orcid.org/0000-0001-9267-8887
Sofia KhanamCalcutta Institute of Pharmaceutical Technology and Allied Health Sciences, Howrah, WB, 711316, India.ORCID http://orcid.org/0000-0002-5201-7387
Nethaji MunirajCentre for Cancer Immunology Research, Children's National Hospital, Children's National Research Institute, 111 Michigan Ave NW, Washington, D.C, 20010, USA. nmuniraj@childrensnational.org.ORCID http://orcid.org/0000-0002-3820-2148
Ananda Vayaravel CassinadaneSri Venkateshwaraa College of Paramedical Sciences, Pondicherry, 605102, India. camvayaravel@gmail.com.ORCID http://orcid.org/0000-0002-2103-8417
Sri Venkateshwaraa Medical College Hospital and Research Centre · INChildren's National · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As per World Health Organization cancer remains as a leading killer disease causing nearly 10 million deaths in 2020. Since the burden of cancer increases worldwide, warranting an urgent search for anti-cancer compounds from natural sources. Secondary metabolites from plants, marine organisms exhibit a novel chemical and structural diversity holding a great promise as therapeutics in cancer treatment. These natural metabolites target only the cancer cells and the normal healthy cells are left unharmed. In the emerging trends of cancer treatment, the natural bioactive compounds have long become a part of cancer chemotherapy. In this review, we have tried to compile about eight bioactive compounds from plant origin viz. combretastatin, ginsenoside, lycopene, quercetin, resveratrol, silymarin, sulforaphane and withaferin A, four marine-derived compounds viz. bryostatins, dolastatins, eribulin, plitidepsin and three microorganisms viz. Clostridium, Mycobacterium bovis and Streptococcus pyogenes with their well-established anticancer potential, mechanism of action and clinical establishments are presented.

Indexed as

Antineoplastic AgentsAntineoplastic Agents, PhytogenicAquatic OrganismsBacteriaBiological ProductsHumansNeoplasmsAntineoplastic AgentsAntineoplastic Agents, PhytogenicBiological ProductsCancerCombretastatinEribulinGinsenosideMycobacterium bovisNovel moleculesPlitidepsin

Identifiers

PMID34982273
OpenAlexW4206421202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.