ArticleRadiology2022
Prediction of Upstaging in Ductal Carcinoma in Situ Based on Mammographic Radiomic Features.
Open access · greenAbstract read
In one paragraph
Article in Radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Artificial intelligence in the radiologic assessment of ductal carcinomaFrontiers in oncology · 2026Pooled it
- MRI-based Radiomic Features for Risk Stratification of Ductal Carcinoma in Situ in a Multicenter Setting (ECOG-ACRIN E4112 Trial).Radiology · 2025Trial
- Channel attention of the image for distinguishing ductal carcinomaGland surgery · 2026Article
- Multicenter development and external validation of clinical-radiomics models to predict surgically confirmed upstaging in biopsy-proven DCIS using DCE-MRI.Journal of applied clinical medical physics · 2026Article
- Prediction of pathologic upstaging in ductal carcinoma in situ using MRI radiomics combined with clinicopathological features.Breast cancer research : BCR · 2026Article
- Prediction of histological grading in ductal carcinomaFrontiers in oncology · 2026Article
- Review
- Radiomics and deep learning model based on X-ray imaging for the assisted diagnosis of early Legg-Calvé-Perthes disease.BMC musculoskeletal disorders · 2025Article
- Super-Resolution Ultrasound Radiomics Can Predict the Upstaging of Ductal Carcinoma In Situ.Cancer medicine · 2025Article
- Preoperative MRI to Predict Upstaging of DCIS to Invasive Cancer at Surgery.Annals of surgical oncology · 2025Observational
- Radiology for Ductal Carcinoma In Situ of the Breast: Updates on Invasive Cancer Progression and Active Monitoring.Korean journal of radiology · 2024Review
- New Frontiers in Breast Cancer Imaging: The Rise of AI.Bioengineering (Basel, Switzerland) · 2024Review
- The features associated with mammography-occult MRI-detected newly diagnosed breast cancer analysed by comparing machine learning models with a logistic regression model.La Radiologia medica · 2024Article
- Application of deep learning on mammographies to discriminate between low and high-risk DCIS for patient participation in active surveillance trials.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- AI analytics can be used as imaging biomarkers for predicting invasive upgrade of ductal carcinoma in situ.Insights into imaging · 2024Article
- Article
- Unenhanced computed tomography radiomics help detect endoleaks after endovascular repair of abdominal aortic aneurysm.European radiology · 2024Article
- Classification performance bias between training and test sets in a limited mammography dataset.PloS one · 2024Article
- Ultrafast MRI and T1 and T2 Radiomics for Predicting Invasive Components in Ductal Carcinoma in Situ Diagnosed With Percutaneous Needle Biopsy.Korean journal of radiology · 2023Article
- An automated surgical decision-making framework for partial or radical nephrectomy based on 3D-CT multi-level anatomical features in renal cell carcinoma.European radiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 7 institutions in 3 countries.
Rui HouFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0002-0348-8772
Lars J GrimmFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0002-3865-3352
Maciej A MazurowskiFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0003-4202-8602
Jeffrey R MarksFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).
Lorraine M KingFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).
Carlo C MaleyFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).
Thomas LynchFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0003-0267-7456
Marja van OirsouwFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).
Keith RogersFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).
Nicholas StoneFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0001-5603-3731
Matthew WallisFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0001-7141-281X
Jonas TeuwenFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0002-1825-1428
Jelle WesselingFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0002-8940-2676
E Shelley HwangFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0002-8571-1148
Joseph Y LoFrom the Departments of Radiology (R.H., L.J.G., J.Y.L.) and Surgery (J.R.M., L.M.K., T.L., E.S.H.), Duke University Medical Center, Box 3513, Durham, NC 27710; Department of Electrical and Computer Engineering, Pratt School of Engineering, Duke University, Durham, NC (R.H.); School of Life Sciences, Arizona State University, Tempe, Ariz (C.C.M.); Cranfield Forensic Institute, Cranfield University, Cranfield, UK (K.R.); School of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, Physics Building, Streatham Campus, University of Exeter, Exeter, UK (N.S.); Cambridge Breast Unit and NIHR Cambridge Biomedical Research Center, Cambridge University Hospitals NHS Trust, Cambridge Biomedical Campus, Cambridge, UK (M.W.); and Netherlands Cancer Institute, Amsterdam, the Netherlands (M.v.O., J.T., J.W.).ORCID 0000-0002-9540-5072
Duke Medical Center · USDuke University · USThe Netherlands Cancer Institute · NLArizona State University · USCambridge University Hospitals NHS Foundation Trust · GBCranfield University · GBUniversity of Exeter · GB
Funding
Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI JOHN N. NORTON · 1985 to 2026
$174.8MPHYLOGENIES of Barrett's Esophagus LineagesP01CA091955 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI GRADY, WILLIAM MALLORY · 2002 to 2019
$35.9MThe Role of the Microbiome in Cancer Suppression and Susceptibility Across SpeciesU54CA217376 · NCI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI SHIBATA, DARRYL K · 2018 to 2022
$8.6MModeling Neoplastic Progression in Barrett's Esophagus - Renewal -2R01CA140657 · NCI · WISTAR INSTITUTE · PI Carlo Maley · 2009 to 2026
$5.0MBreast Cancer Detection ConsortiumU01CA214183 · NCI · DUKE UNIVERSITY · PI MARKS, JEFFREY R., TANG, CHA-MEI · 2016 to 2021
$2.4M(PQC3) Genomic Diversity and Microenvironment as Drivers of Metastasis in DCISR01CA185138 · NCI · DUKE UNIVERSITY · PI HWANG, E.SHELLEY, MALEY, CARLO · 2014 to 2017
$2.0MCancer Research UKDepartment of Health BRC-1215-20014Medical Research Council MR/T000406/1NCI NIH HHS P01 CA091955NCI NIH HHS P30 CA014236NCI NIH HHS R01 CA140657NCI NIH HHS R01 CA185138NCI NIH HHS U01 CA214183NCI NIH HHS U54 CA217376
Abstract
Background Improving diagnosis of ductal carcinoma in situ (DCIS) before surgery is important in choosing optimal patient management strategies. However, patients may harbor occult invasive disease not detected until definitive surgery. Purpose To assess the performance and clinical utility of mammographic radiomic features in the prediction of occult invasive cancer among women diagnosed with DCIS on the basis of core biopsy findings. Materials and Methods In this Health Insurance Portability and Accountability Act-compliant retrospective study, digital magnification mammographic images were collected from women who underwent breast core-needle biopsy for calcifications that was performed at a single institution between September 2008 and April 2017 and yielded a diagnosis of DCIS. The database query was directed at asymptomatic women with calcifications without a mass, architectural distortion, asymmetric density, or palpable disease. Logistic regression with regularization was used. Differences across training and internal test set by upstaging rate, age, lesion size, and estrogen and progesterone receptor status were assessed by using the Kruskal-Wallis or χ
Indexed as
Breast NeoplasmsCalcinosisCarcinoma, Ductal, BreastCarcinoma in SituCarcinoma, Intraductal, NoninfiltratingAdultAgedAged, 80 and overFemaleHumansMaleMammographyMiddle AgedRetrospective Studies
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.