Evidence map›Paper›PMID 34981882›Full record

ArticleJournal of applied microbiology2022

Residual antimicrobial coating efficacy against SARS-CoV-2.

Rachael L Hardison, Shawn P Ryan, Rebecca A Limmer, Margaret Crouse, Sarah W Nelson, Daniela Barriga, Jessica M Ghere, Michael J Stewart, Sang Don Lee, Brian M Taylor and 3 more

Abstract read
In one paragraph

Article in Journal of applied microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rachael L HardisonBattelle Memorial Institute, Columbus, Ohio, USA.
Shawn P RyanUS EPA, Research Triangle Park, North Carolina, USA.
Rebecca A LimmerBattelle Eastern Science & Technology Center, Aberdeen, Maryland, USA.
Margaret CrouseBattelle Eastern Science & Technology Center, Aberdeen, Maryland, USA.
Sarah W NelsonBattelle Memorial Institute, Columbus, Ohio, USA.
Daniela BarrigaBattelle Memorial Institute, Columbus, Ohio, USA.
Jessica M GhereBattelle Memorial Institute, Columbus, Ohio, USA.
Michael J StewartUS EPA, Research Triangle Park, North Carolina, USA.
Sang Don LeeUS EPA, Research Triangle Park, North Carolina, USA.
Brian M TaylorBattelle Eastern Science & Technology Center, Aberdeen, Maryland, USA.
Ryan R JamesBattelle Memorial Institute, Columbus, Ohio, USA.
Michael W CalfeeUS EPA, Research Triangle Park, North Carolina, USA.ORCID https://orcid.org/0000-0001-6544-329X
Megan W HowardBattelle Memorial Institute, Columbus, Ohio, USA.

Funding

EPA EP-C-16-014Intramural EPA EPA999999United States Environmental Protection Agency 68HERC20F0231
6 · The paper itself

Abstract

aimsThis study evaluated the residual efficacy of commercially available antimicrobial coatings or films against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on non-porous surfaces. METHODS AND

resultsProducts were applied to stainless steel or ABS plastic coupons and dried overnight. Coupons were inoculated with SARS-CoV-2 in the presence of 5% soil load. Recovered infectious SARS-CoV-2 was quantified by TCID50 assay. Tested product efficacies ranged from <1.0 to >3.0 log

conclusionsThe residual antimicrobial products tested showed varied effectiveness against SARS-CoV-2 as a function of product tested. Several products were identified as efficacious against SARS-CoV-2 on both stainless steel and ABS plastic surfaces under the conditions evaluated. Differences in observed efficacy may be due to variation in active ingredient formulation; efficacy is, therefore, difficult to predict based upon listed active ingredient and its concentration. SIGNIFICANCE AND IMPACT: This study highlights the formulation-specific efficacy of several products against SARS-CoV-2 and may inform future development of residual antiviral products for use on non-porous surfaces. The identification of antimicrobial coatings or films showing promise to inactivate SARS-CoV-2 suggests that these products may be worth future testing and consideration.

Indexed as

Anti-Infective AgentsCOVID-19 Drug TreatmentAnti-Bacterial AgentsAntiviral AgentsHumansSARS-CoV-2Anti-Bacterial AgentsAnti-Infective AgentsAntiviral Agentsantimicrobial coatingCOVID-19disinfectionSARS-CoV-2virucide

Identifiers

PMID34981882
PMCPMC9547327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.