Evidence map›Paper›PMID 34981758›Full record

ReviewActa crystallographica. Section D, Structural biology2022

Best practices for time-resolved serial synchrotron crystallography.

Eike C Schulz, Briony A Yorke, Arwen R Pearson, Pedram Mehrabi

Abstract readReview
In one paragraph

Review in Acta crystallographica. Section D, Structural biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eike C SchulzInstitute for Nanostructure and Solid State Physics, Universität Hamburg, HARBOR, Luruper Chaussee 149, 22761 Hamburg, Germany.
Briony A YorkeSchool of Chemistry and Bioscience, University of Bradford, Bradford BD7 1DP, United Kingdom.ORCID 0000-0002-1868-8435
Arwen R PearsonInstitute for Nanostructure and Solid State Physics, Universität Hamburg, HARBOR, Luruper Chaussee 149, 22761 Hamburg, Germany.ORCID 0000-0001-8499-7490
Pedram MehrabiInstitute for Nanostructure and Solid State Physics, Universität Hamburg, HARBOR, Luruper Chaussee 149, 22761 Hamburg, Germany.

Funding

Academy of Medical Sciences SBF006D4Bundesministerium für Bildung und Forschung 05K16GU1Bundesministerium für Bildung und Forschung 05K19GU1Deutsche Forschungsgemeinschaft 451079909Deutsche Forschungsgemeinschaft 458246365Deutsche Forschungsgemeinschaft EXC1074Deutsche Forschungsgemeinschaft EXC2056
6 · The paper itself

Abstract

With recent developments in X-ray sources, instrumentation and data-analysis tools, time-resolved crystallographic experiments, which were originally the preserve of a few expert groups, are becoming simpler and can be carried out at more radiation sources, and are thus increasingly accessible to a growing user base. However, these experiments are just that: discrete experiments, not just `data collections'. As such, careful planning and consideration of potential pitfalls is required to enable a successful experiment. Here, some of the key factors that should be considered during the planning and execution of a time-resolved structural study are outlined, with a particular focus on synchrotron-based experiments.

Indexed as

SynchrotronsAnimalsCrystallography, X-RayData AnalysisEnzymesHumansEnzymesmechanistic structural biologyserial crystallographySSXstructural enzymologytime-resolved crystallography

Identifiers

PMID34981758
PMCPMC8725164

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.