Evidence map›Paper›PMID 34981741›Full record

ArticleEuropean thyroid journal2022

2022 ETA Consensus Statement: What are the indications for post-surgical radioiodine therapy in differentiated thyroid cancer?

Furio Pacini, Dagmar Fuhrer, Rossella Elisei, Daria Handkiewicz-Junak, Sophie Leboulleux, Markus Luster, Martin Schlumberger, Johannes W Smit

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in European thyroid journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06134830 (Clinical Outcome and Quality of Life in Differentiated Thyroid Cancer Patients Treated With Different Doses of Radioactive Iodine.), which is not on this map. Cited by 100 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 3 pooled it
18.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06134830 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Outcome and Quality of Life in Differentiated Thyroid Cancer Patients Treated With Different Doses of Radioactive Iodine.

TypeobservationalSponsorAssiut UniversityRan2024 to 2027Enrolled100ConditionsThyroid CancerArmsRAI
3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 3 syntheses or guidelines pooled it, 144 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Review
  5. Article
  6. Optimal timing of post-therapeutic [BMC medical imaging · 2026
    Review
  7. [New developments in endocrinology/diabetology].Innere Medizin (Heidelberg, Germany) · 2026
    Review
  8. Article
  9. Article
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  18. The Role ofMedical sciences (Basel, Switzerland) · 2026
    Review
  19. Review
  20. Review

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 5 countries.

Furio PaciniSection of Endocrinology, University of Siena, Siena, Italy.
Dagmar FuhrerDepartment of Endocrinology, Diabetes and Metabolism, West German Cancer Centre (WTZ), University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Rossella EliseiSection of Endocrinology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Daria Handkiewicz-JunakDepartment of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland.
Sophie LeboulleuxGustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France.
Markus LusterDepartment of Nuclear Medicine, University Hospital Marburg, Marburg, Germany.
Martin SchlumbergerGustave Roussy Cancer Campus and University Paris-Saclay, Villejuif, Cedex, France.
Johannes W SmitRadboud University Medical Center, Nijmegen, Netherlands.
Institut Gustave Roussy · FRPhilipps University of Marburg · DERadboud University Nijmegen · NLThe Maria Sklodowska-Curie National Research Institute of Oncology · PLUniversity of Pisa · ITUniversity of Siena · ITWest German Heart and Vascular Center Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern use of post-operative radioactive iodine (RAI) treatment for differentiated thyroid cancer (DTC) should be implemented in line with patients' risk stratification. Although beneficial effects of radioiodine are undisputed in high-risk patients, controversy remains in intermediate-risk and some low-risk patients. Since the last consensus on post-surgical use of RAI in DTC patients, new retrospective data and results of prospective randomized trials have been published, which have allowed the development of a new European Thyroid Association (ETA) statement for the indications of post-surgical RAI therapy in DTC. Questions about which patients are candidates for RAI therapy, which activities of RAI can be used, and which modalities of pre-treatment patient preparation should be used are addressed in the present guidelines.

Indexed as

differentiated thyroid cancerindicationsradioiodinetreatment

Identifiers

PMID34981741
PMCPMC9142814
OpenAlexW3209002826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.