Evidence map›Paper›PMID 34981686›Full record

ArticleCroatian medical journal2021

The cost of care for people living with stable HIV in Croatia and the efficiency of EmERGE.

Eduard J Beck, Sundhiya Mandalia, Platonas Yfantopoulos, Christopher Jones, Stephen Bremner, Jennifer Whetham, Ivana Benković, Šime Zekan, Josip Begovac

Open access · diamondAbstract read
In one paragraph

Article in Croatian medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Eduard J BeckEduard J. Beck, c/- NPMS-HHC CIC, 21 Bedford Square, London, United Kingdom, WC1B 3HH, ejbeckphase2017@gmail.com.
Sundhiya Mandalia
Platonas Yfantopoulos
Christopher Jones
Stephen Bremner
Jennifer Whetham
Ivana Benković
Šime Zekan
Josip Begovac
Brighton and Sussex Medical School · GBUniversity Hospital Centre Zagreb · HRFaculty of Public Health · GBUniversity Hospital for Infectious Diseases "Dr Fran Mihaljevic" · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo estimate the cost-effectiveness of the EmERGE Pathway of Care for medically stable people living with HIV (PLHIV) at the University Hospital for Infectious Diseases (UHID), Zagreb. The Pathway includes a mobile application enabling individuals to communicate with their caregivers.

methodsThis study involving 293 participants collected data on the use of HIV outpatient services one year before and after EmERGE implementation. In departments supporting HIV outpatients, a micro-costing exercise was performed to calculate unit costs. These were combined with mean use of HIV services per patient year (MPPY) to estimate average annual costs. Primary outcomes were CD4 count, viral load, and secondary outcomes were patient activation, PAM13; and quality of life, PROQOL-HIV. Information on out-of-pocket expenditures was also collected.

resultsOutpatient visits decreased by 17%, from 4.0 (95% CI 3.8-4.3) to 3.3 MPPY (95% CI 3.1-3.5). Tests, including CD4 count, decreased, all contributing to a 33% reduction of annual costs: 7139 HRK (95% CI 6766-7528) to 4781 HRK (95% CI 4504-5072). Annual costs including anti-retroviral drugs (ARVs) decreased by 5%: 43101 HRK (95% CI 42728-43,490) to 40 743 HRK (95% CI 40466-41,034). ARVs remain the main cost driver in stable PLHIV. Primary and secondary outcomes did not change substantially between periods.

conclusionEmERGE Pathway was a cost-saving intervention associated with changes in management, and a reduction in outpatient visits, tests, and costs. ARV costs dominated costs. Future efficiencies are possible if EmERGE is introduced to other PLHIV across the UHID and if ARV prices are reduced.

Indexed as

HIV InfectionsQuality of LifeCD4 Lymphocyte CountCost-Benefit AnalysisCroatiaHumans

Identifiers

PMID34981686
PMCPMC8771231
OpenAlexW4206894138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.