Evidence map›Paper›PMID 34981481›Full record

ReviewAdvances in experimental medicine and biology2021

Protective Effects of Curcumin in the Reproductive System: Anti-toxic, Semen Cryopreservative, and Contraceptive Actions.

Maryam Matbou Riahi, Behzad Behnam, Neil C Henney, Tannaz Jamialahmadi, Amirhossein Sahebkar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Maryam Matbou RiahiHeart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Behzad BehnamHerbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman, Iran. behnamb@kmu.ac.ir.
Neil C HenneyPharmacy & Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
Tannaz JamialahmadiDepartment of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran.
Amirhossein SahebkarBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. sahebkara@mums.ac.ir.
Isfahan University of Medical Sciences · IRIslamic Azad University Quchan · IRKerman University of Medical Sciences · IRLiverpool John Moores University · GBMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human daily exposure to various chemical and biological agents is growing due to modern life, and most of these chronic or acute exposures lead to important recognized toxicities. Multiple tissues and body systems could be affected following these exposures and among them is the human reproductive system, which is very vulnerable to toxins. Here we focus mainly on the male reproductive system, and available data show that various exogenous materials could have negative effects on male reproductive parameters. Interestingly, the well-known antioxidant natural product curcumin may have properties which could diminish these toxic effects. Curcumin has also shown some promise in the cryoprotection of sperm samples through its antioxidant potential. Finally, limited data exists on the putative contraceptive activity of curcumin. This narrative review aims to appraise the activity of curcumin within these topics through the available data.

Indexed as

CurcuminSemenAntioxidantsContraceptive AgentsHumansMaleSpermatozoaSperm MotilityAntioxidantsContraceptive AgentsCurcuminAntioxidantAnti-toxicContraceptiveCurcuminMale reproductive toxicitySperm cryopreservation

Identifiers

PMID34981481
OpenAlexW4205994700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.