Evidence map›Paper›PMID 34981472›Full record

ReviewAdvances in experimental medicine and biology2021

The Multifaceted Actions of Curcumin in Obesity.

Vanessa Bianconi, Matteo Pirro, Seyed Mohammad Hassan Moallem, Muhammed Majeed, Paola Bronzo, Marco D'Abbondanza, Tannaz Jamialahmadi, Amirhossein Sahebkar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Epigenetics of Childhood Obesity.Hormone research in paediatrics · 2026
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Vanessa BianconiUnit of Internal Medicine, Angiology, and Arteriosclerosis Diseases, Department of Medicine, University of Perugia, Perugia, Italy.
Matteo PirroUnit of Internal Medicine, Angiology, and Arteriosclerosis Diseases, Department of Medicine, University of Perugia, Perugia, Italy.
Seyed Mohammad Hassan MoallemSchool of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Muhammed MajeedSabinsa Corporation, East Windsor, NJ, USA.
Paola BronzoUnit of Internal Medicine, Angiology, and Arteriosclerosis Diseases, Department of Medicine, University of Perugia, Perugia, Italy.
Marco D'AbbondanzaUnit of Internal Medicine, Angiology, and Arteriosclerosis Diseases, Department of Medicine, University of Perugia, Perugia, Italy.
Tannaz JamialahmadiDepartment of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran.
Amirhossein SahebkarBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. sahebkara@mums.ac.ir.
University of Perugia · ITMashhad University of Medical Sciences · IRSabin Vaccine Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity remains a pervasive health concern worldwide with concomitant comorbidities such as cardiovascular diseases, diabetes, inflammation, and other metabolic disorders. A wealth of data validates dietary and lifestyle modifications such as restricting caloric intake and increasing physical activity to slow the obesity development. Recently, the advent of phytochemicals such as curcumin, the active ingredient in turmeric, has attracted considerable research interest in tracking down their possible effects in protection against obesity and obesity-related comorbidities. According to the existing literature, curcumin may regulate lipid metabolism and suppress chronic inflammation interacting with white adipose tissue, which plays a central role in the complications associated with obesity. Curcumin also inhibits the differentiation of adipocyte and improves antioxidant properties. In the present review, we sought to deliberate the possible effects of curcumin in downregulating obesity and curtailing the adverse health effects of obesity.

Indexed as

CurcuminAdipocytesAdipose Tissue, WhiteHumansInflammationObesityCurcuminAdiposityCurcuminInflammationMetabolism

Identifiers

PMID34981472
OpenAlexW4206538663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.