Evidence map›Paper›PMID 34981435›Full record

SynthesisJournal of neurovirology2022

Cerebral and spinal cord changes observed through magnetic resonance imaging in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis: a systematic review.

Ana Patrícia Bastos Ferreira, Ana Dolores Firmino Santos do Nascimento, Pedro Augusto Sampaio Rocha-Filho

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of neurovirology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ana Patrícia Bastos FerreiraPost-Graduation Program in Neuropsychiatry and Behavioral Sciences (Posneuro), Federal University of Pernambuco (UFPE), Recife, Brazil.ORCID 0000-0003-0975-1014
Ana Dolores Firmino Santos do NascimentoPost-Graduation Program in Neuropsychiatry and Behavioral Sciences (Posneuro), Federal University of Pernambuco (UFPE), Recife, Brazil.ORCID 0000-0003-0525-1864
Pedro Augusto Sampaio Rocha-FilhoDivision of Neuropsychiatry, Federal University of Pernambuco (UFPE), Recife, Brazil. pedroasampaio@gmail.com.ORCID 0000-0001-5725-2637
Universidade Federal de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To verify brain and spinal changes using magnetic resonance imaging in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis. This was a systematic review. The descriptors used were tropical spastic paraparesis and magnetic resonance image. The keyword HTLV-1-associated myelopathy was also used. Twenty-three articles were included: 16 detected brain changes and 18 detected spinal changes. White matter lesions were the most frequent finding in the brain. Brain injuries were most frequently identified in the periventricular region, in the subcortical region, in the centrum semiovale, in the brain stem, and corpus callosum. Atrophy was the most frequent finding of the spinal cord, affecting the thoracic and cervical regions, and was associated with a longer evolution of myelopathy. White matter lesions in these regions were also observed. Cortical white matter lesions and thoracic spinal cord atrophy were the most frequently reported changes in patients with HTLV-1-associated myelopathy.

Indexed as

Human T-lymphotropic virus 1Nervous System DiseasesParaparesis, Tropical SpasticAtrophyBrainHumansMagnetic Resonance ImagingSpinal CordBrainHuman T-lymphotropic virus 1Magnetic resonance imagingSpinal cordTropical spastic paraparesis

Identifiers

PMID34981435
OpenAlexW4205727276

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.