Evidence map›Paper›PMID 34981358›Full record

ArticleJournal of general internal medicine2022

Implementation of an Intensive Telehealth Intervention for Rural Patients with Clinic-Refractory Diabetes.

Elizabeth A Kobe, Allison A Lewinski, Amy S Jeffreys, Valerie A Smith, Cynthia J Coffman, Susanne M Danus, Elisabeth Sidoli, Beth D Greck, Leanne Horne, David R Saxon and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
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  6. Article
  7. SGLT2i and GLP-1RA Use in the USA.Journal of general internal medicine · 2026
    Article
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  11. Observational
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  19. Factors Influencing Compliance to Follow-up Visits in Orthopaedic Surgery.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 9 institutions in 1 country.

Elizabeth A KobeDuke University School of Medicine, Durham, NC, USA.
Allison A LewinskiCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Amy S JeffreysCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Valerie A SmithCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Cynthia J CoffmanCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Susanne M DanusCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Elisabeth SidoliWestern North Carolina Veteran Affairs Health Care System, Asheville, NC, USA.
Beth D GreckWestern North Carolina Veteran Affairs Health Care System, Asheville, NC, USA.
Leanne HorneVISN 19 Rocky Mountain Regional, Denver, CO, USA.
David R SaxonDivision of Endocrinology, Metabolism and Diabetes, University of Colorado School of Medicine, Aurora, CO, USA.
Susan ShookNew Mexico Veteran Affairs Health Care System, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Lina E AguirreNew Mexico Veteran Affairs Health Care System, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Mary G EsquibelNew Mexico Veteran Affairs Health Care System, University of New Mexico School of Medicine, Albuquerque, NM, USA.
Clarene EvensonMontana Veteran Affairs Health Care System, Kalispell, MT, USA.
Christopher ElizagarayMontana Veteran Affairs Health Care System, Kalispell, MT, USA.
Vivian NelsonVeterans Affairs Central Ohio Healthcare System, Columbus, OH, USA.
Amanda ZeekVeterans Affairs Central Ohio Healthcare System, Columbus, OH, USA.
William G WeppnerDivision of General Internal Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Stephanie ScodellaroBoise Veteran Affairs Medical Center, Boise, ID, USA.
Cassie J PerdewBoise Veteran Affairs Medical Center, Boise, ID, USA.
George L JacksonCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Karen SteinhauserCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Hayden B BosworthDepartment of Psychiatry & Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.
David EdelmanCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Matthew J CrowleyCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA. matthew.crowley@duke.edu.ORCID 0000-0002-6205-4536
Duke University · USUniversity of New Mexico · USBoise VA Medical Center · USDurham VA Health Care System · USVA Montana Health Care System · USVA Northeast Ohio Healthcare System · USUniversity of Washington · USVA Rocky Mountain Network · USVeterans Health Administration · US

Funding

Research Project 3U54MD012530 · NIMHD · DUKE UNIVERSITY · PI JOHNSON, KIMBERLY S. · 2017 to 2022
$8.8M
NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
EXpanding Technology-Enabled, Nurse-Delivered Chronic Disease Care (EXTEND)R01NR019594 · NINR · DUKE UNIVERSITY · PI CROWLEY, MATTHEW J., SHAW, RYAN JEFFREY · 2021 to 2025
$3.4M
Couple Communication Skills Training for Advanced CancerR01CA229425 · NCI · DUKE UNIVERSITY · PI PORTER, LAURA S · 2020 to 2024
$3.1M
The Spreading Healthcare Access, Activities, Research and Knowledge (SHAARK) QUERI ProgramI50HX003198 · VA · DURHAM VA MEDICAL CENTER · PI CROWLEY, MATTHEW J., CUTRONA, SARAH LELEIKO · 2021 to 2021
–
HSR&D Senior Research Career Scientist AwardIK6HX003161 · VA · DURHAM VA MEDICAL CENTER · PI Hayden B Bosworth · 2020 to 2026
–
Tailored, eHealth-based Management for Persistent Poorly-Controlled DiabetesIK2HX001514 · VA · DURHAM VA MEDICAL CENTER · PI CROWLEY, MATTHEW J. · 2019 to 2020
–
HSRD VA CIN 13-410HSRD VA IK2 HX001514HSRD VA IK6 HX003161NCATS NIH HHS TL1 TR002555NCI NIH HHS R01 CA229425NIMHD NIH HHS U54 MD012530NINR NIH HHS R01 NR019594
6 · The paper itself

Abstract

backgroundRural patients with type 2 diabetes (T2D) may experience poor glycemic control due to limited access to T2D specialty care and self-management support. Telehealth can facilitate delivery of comprehensive T2D care to rural patients, but implementation in clinical practice is challenging.

objectiveTo examine the implementation of Advanced Comprehensive Diabetes Care (ACDC), an evidence-based, comprehensive telehealth intervention for clinic-refractory, uncontrolled T2D. ACDC leverages existing Veterans Health Administration (VHA) Home Telehealth (HT) infrastructure, making delivery practical in rural areas.

designMixed-methods implementation study.

participants230 patients with clinic-refractory, uncontrolled T2D.

interventionACDC bundles telemonitoring, self-management support, and specialist-guided medication management, and is delivered over 6 months using existing VHA HT clinical staffing/equipment. Patients may continue in a maintenance protocol after the initial 6-month intervention period. MAIN MEASURES: Implementation was evaluated using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. The primary effectiveness outcome was hemoglobin A1c (HbA1c). KEY

resultsFrom 2017 to 2020, ACDC was delivered to 230 patients across seven geographically diverse VHA sites; on average, patients were 59 years of age, 95% male, 80% white, and 14% Hispanic/Latinx. Patients completed an average of 10.1 of 12 scheduled encounters during the 6-month intervention period. Model-estimated mean baseline HbA1c was 9.56% and improved to 8.14% at 6 months (- 1.43%, 95% CI: - 1.64, - 1.21; P < .001). Benefits persisted at 12 (- 1.26%, 95% CI: - 1.48, - 1.05; P < .001) and 18 months (- 1.08%, 95% CI - 1.35, - 0.81; P < .001). Patients reported increased engagement in self-management and awareness of glycemic control, while clinicians and HT nurses reported a moderate workload increase. As of this submission, some sites have maintained delivery of ACDC for up to 4 years.

conclusionsWhen strategically designed to leverage existing infrastructure, comprehensive telehealth interventions can be implemented successfully, even in rural areas. ACDC produced sustained improvements in glycemic control in a previously refractory population.

Indexed as

Diabetes Mellitus, Type 2TelemedicineAmbulatory Care FacilitiesFemaleGlycated HemoglobinHumansMaleRural PopulationGlycated Hemoglobindiabetes mellitus, type 2health services researchimplementation sciencerural healthtelemedicine

Identifiers

PMID34981358
PMCPMC8722663
OpenAlexW4206609896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.