ArticleJournal of general internal medicine2022
Frailty and Survival After In-Hospital Cardiopulmonary Resuscitation.
Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Checklist-Guided Code Status Discussions in Patients for Whom Cardiopulmonary Resuscitation Is Considered Futile: An Analysis of a Randomized Clinical Trial.JAMA network open · 2025Trial
- Prognostic Value of Temporalis Muscle Thickness for Predicting Mortality in Patients with Emergency Department Cardiac Arrest.Medicina (Kaunas, Lithuania) · 2026Article
- Investigation of Bisphosphonate Therapy for Osteoporosis: A Single-Center Cross-Sectional Study.Journal of general and family medicine · 2026Article
- Nationwide analysis of mortality predictors following in-hospital cardiac arrest in older Thai adults, 2016-2024.Resuscitation plus · 2026Article
- Combining the National Early Warning Score 2 with Frailty Assessment to Identify Patients at Risk of In-Hospital Cardiac Arrest: A Descriptive Exploratory Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Treatment limitations and participation in elderly patients - the gap between medical-ethical guidelines and clinical practice: a cross sectional-study from Sweden.BMC geriatrics · 2025Article
- Resuscitation discussion practices: a survey of European geriatricians.European geriatric medicine · 2025Article
- Temporalis muscle thickness correlates with premorbid frailty in patients resuscitated from cardiac arrest.Resuscitation · 2025Article
- Influences on the duration and success of out-of-hospital resuscitation of geriatric patients over 80 years of age - a retrospective evaluation.BMC emergency medicine · 2024Article
- Accuracy of frailty instruments in predicting outcomes following perioperative cardiac arrest.Resuscitation · 2024Article
- Perceptions on Specialist Palliative Care Involvement During and After Cardiopulmonary Resuscitation: A Qualitative Study.Critical care explorations · 2024Article
- Comprehensive geriatric assessment as an essential tool to register or update DNR codes in a tertiary care hospital.European geriatric medicine · 2024Article
- A comparison between the effects of simulation of basic CPR training and workshops on firefighters' knowledge and skills: experimental study.BMC medical education · 2024Article
- Cardio pulmonary resuscitation (CPR) in the frail and those with multiple health conditions: Outcomes before and during the COVID pandemic.Clinical medicine (London, England) · 2024Article
- Frailty and Outcomes Following Cardiopulmonary Resuscitation for Perioperative Cardiac Arrest.JAMA network open · 2023Article
- Mortality Risks after Two Years in Frail and Pre-Frail Older Adults Admitted to Hospital.Journal of clinical medicine · 2023Article
- Feasibility of implementing a telephone-based frailty assessment.Journal of the American Geriatrics Society · 2022Article
- Outcomes in adults living with frailty receiving cardiopulmonary resuscitation: A systematic review and meta-analysis.Resuscitation plus · 2022Article
- 30-day mortality following COVID-19 and influenza hospitalization among US veterans aged 65 and older.Journal of the American Geriatrics Society · 2022Article
- "If I Become a Vegetable, Then no": A Thematic Analysis of How Patients and Physicians Refer to Prognosis When Discussing Cardiopulmonary Resuscitation.Gerontology & geriatric medicineArticle
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOlder adults face high mortality following resuscitation efforts for in-hospital cardiac arrest. Less is known about the role of frailty in survival to discharge after in-hospital cardiopulmonary resuscitation.
objectiveTo investigate whether frailty, measured by the Clinical Frailty Scale, is associated with mortality after cardiopulmonary resuscitation following in-hospital cardiac arrest in older adults in the USA.
designRetrospective cohort study.
participantsPatients ≥ 65 years who had undergone cardiopulmonary resuscitation during an inpatient admission at two urban academic hospitals and three suburban community hospitals within a Boston area healthcare system from January 2018-January 2020. Patients with Clinical Frailty Scale scores 1-3 were considered not frail, 4-6 were considered very mildly, mildly, and moderately frail, respectively, and 7-9 were considered severely frail. MAIN MEASURES: In-hospital mortality after cardiopulmonary resuscitation. KEY
resultsAmong 324 patients who underwent cardiopulmonary resuscitation following in-hospital cardiac arrest, 73.1% experienced in-hospital mortality. Patients with a Clinical Frailty Scale score of 1-3 had 54% in-hospital mortality, which increased to 66%, 78%, 84%, and 84% for those with a Clinical Frailty Scale score of 4, 5, 6, and 7-9, respectively (p = 0.001). After adjusting for age, sex, race, and Charlson Comorbidity Index, higher frailty scores were significantly associated with higher odds of in-hospital mortality. Compared to those with a Clinical Frailty Scale score of 1-3, odds ratios (95% CI) for in-hospital mortality for patients with a Clinical Frailty Scale score of 4, 5, 6, and 7-9 were 1.6 (0.8-3.3), 3.0 (1.3-7.1), 4.4 (1.9-9.9), and 4.6 (1.8-11.8), respectively (p = 0.001).
conclusionsHigher levels of frailty are associated with increased mortality after in-hospital cardiopulmonary resuscitation in older adults. Clinicians may consider using the Clinical Frailty Scale to help guide goals of care conversations, including discussion of code status, in this patient population.
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