Evidence map›Paper›PMID 34981149›Full record

ArticleAnalytical and bioanalytical chemistry2022

Coupling immuno-magnetic capture with LC-MS/MS(MRM) as a sensitive, reliable, and specific assay for SARS-CoV-2 identification from clinical samples.

Ofir Schuster, Yafit Atiya-Nasagi, Osnat Rosen, Anat Zvi, Itai Glinert, Amir Ben Shmuel, Shay Weiss, Orly Laskar, Liron Feldberg

Open access · bronzeAbstract readValidation Study
In one paragraph

Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ofir Schuster *Department of Infectious Diseases, Israel Institute for Biological Research (IIBR), Ness Ziona, Israel. ofirsc@iibr.gov.il.
Yafit Atiya-NasagiDepartment of Infectious Diseases, Israel Institute for Biological Research (IIBR), Ness Ziona, Israel.
Osnat RosenDepartment of Biotechnology, IIBR, Ness Ziona, Israel.
Anat ZviDepartment of Biochemistry and Molecular Genetics, IIBR, Ness Ziona, Israel.
Itai GlinertDepartment of Infectious Diseases, Israel Institute for Biological Research (IIBR), Ness Ziona, Israel.
Amir Ben ShmuelDepartment of Infectious Diseases, Israel Institute for Biological Research (IIBR), Ness Ziona, Israel.
Shay WeissDepartment of Infectious Diseases, Israel Institute for Biological Research (IIBR), Ness Ziona, Israel.
Orly LaskarDepartment of Infectious Diseases, Israel Institute for Biological Research (IIBR), Ness Ziona, Israel.
Liron Feldberg *Department of Analytical Chemistry, IIBR, Ness Ziona, Israel. lironf@iibr.gov.il.ORCID http://orcid.org/0000-0003-3612-1421
Israel Institute for Biological Research · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, numerous diagnostic approaches from different disciplines have been developed for SARS-CoV-2 diagnosis to monitor and control the COVID-19 pandemic. These include MS-based assays, which provide analytical information on viral proteins. However, their sensitivity is limited, estimated to be 5 × 10

Indexed as

Amino Acid SequenceAntibodies, ViralBiomarkersChromatography, LiquidCOVID-19COVID-19 TestingHumansImmunomagnetic SeparationNasopharynxPeptidesSARS-CoV-2Sensitivity and SpecificityTandem Mass SpectrometryAntibodies, ViralBiomarkersPeptidesClinical samplesImmunomagnetic captureLC–MS/MS(MRM)SARS-CoV-2Signal to noise ratio

Identifiers

PMID34981149
PMCPMC8723902
OpenAlexW4206114905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.