Evidence map›Paper›PMID 34980769›Full record

ArticleExperimental animals2022

Characterization of single nucleotide polymorphisms for a forward genetics approach using genetic crosses in C57BL/6 and BALB/c substrains of mice.

Ikuo Miura, Yoshiaki Kikkawa, Shumpei P Yasuda, Akiko Shinogi, Daiki Usuda, Vivek Kumar, Joseph S Takahashi, Masaru Tamura, Hiroshi Masuya, Shigeharu Wakana

Abstract read
In one paragraph

Article in Experimental animals, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ikuo MiuraDivision of Molecular Genetics, Department of Cooperative Graduate School, School of Medicine, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata-shi, Niigata 951-8510, Japan.
Yoshiaki KikkawaDivision of Molecular Genetics, Department of Cooperative Graduate School, School of Medicine, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata-shi, Niigata 951-8510, Japan.
Shumpei P YasudaDeafness Project, Department of Basic Medical Sciences, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.
Akiko ShinogiTechnology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan.
Daiki UsudaTechnology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan.
Vivek KumarThe Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, United States.
Joseph S TakahashiDepartment of Neuroscience, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390, United States.
Masaru TamuraTechnology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan.
Hiroshi MasuyaIntegrated Bioresource Information Division, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan.
Shigeharu WakanaTechnology and Development Team for Mouse Phenotype Analysis, Japan Mouse Clinic, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan.

Funding

Sequencing Mutant Mice With Altered Cocaine ResponsesU01DA041668 · NIDA · JACKSON LABORATORY · PI KUMAR, VIVEK · 2016 to 2020
$2.8M
Genetic basis of nicotine withdrawal in a reduced complexity crossU01DA045299 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DAMAJ, M. IMAD, KUMAR, VIVEK · 2018 to 2022
$2.7M
NIDA NIH HHS U01 DA041668NIDA NIH HHS U01 DA045299
6 · The paper itself

Abstract

Forward genetics is a powerful approach based on chromosomal mapping of phenotypes and has successfully led to the discovery of many mouse mutations in genes responsible for various phenotypes. Although crossing between genetically remote strains can produce F

Indexed as

Polymorphism, Single NucleotideAnimalsCrosses, GeneticMiceMice, Inbred BALB CMice, Inbred C57BLPhenotypeBALB/cC57BL/6genotypingsingle nucleotide polymorphismsubstrain

Identifiers

PMID34980769
PMCPMC9130033

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.