SynthesisJournal of medical ethics2022
Fertility preservation for transgender children and young people in paediatric healthcare: a systematic review of ethical considerations.
Synthesis in Journal of medical ethics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Gender-Affirming Surgery as a Treatment Option for Gender Dysphoria in Adults: A Systematic Review of Ethical Reasons.Healthcare (Basel, Switzerland) · 2026Review
- Ethical analysis of the European normative framework on fertility preservation.BMC medical ethics · 2026Article
- Ethics of non-oncological fertility preservation from the perspective of the four principles of bioethics.Frontiers in reproductive health · 2026Article
- Ethical perspectives of fertility preservation through experts' opinions.Frontiers in reproductive health · 2026Article
- A scoping review of the ethical issues in gender-affirming care for transgender and gender-diverse individuals.BMC medical ethics · 2025Article
- Parental perspectives on fertility preservation for their trans and gender-expansive children: Reflections on complexities of autonomy, support, and societal realities.International journal of transgender health · 2025Article
- Fertility preservation methods in children with the risk of female hypogonadism - possibilities and limitations.Pediatric endocrinology, diabetes, and metabolism · 2025Review
- Shared decision-making in adolescent healthcare: a literature review of ethical considerations.European journal of pediatrics · 2024Review
- Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile fertility preservation is recommended practice for paediatric oncology patients, it is increasingly being considered for transgender children and young people in paediatric care. This raises ethical issues for clinicians, particularly around consent and shared decision-making in this new area of healthcare.
methodsA systematic review of normative literature was conducted across four databases in June 2020 to capture ethical considerations related to fertility counselling and preservation in paediatric transgender healthcare. The text of included publications was analysed inductively, guided by the Qualitative Analysis Guide of Leuven.
resultsTwenty-four publications were identified for inclusion. Four key ethical considerations emerged from this literature: access to fertility preservation, conscientious objection, decision-making capacity of children and young people, and shared decision-making.
conclusionIn the identified literature, there is consensus that transgender children and young people should not be refused access to fertility preservation services solely due to their gender identity, and that clinicians with conscientious objections to fertility preservation for this group have an obligation to refer on to willing providers. Factors that create ethical complexity in this area of paediatric care include the child's age, mental health, and parents' views.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.