ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022
Direct Cochlear Recordings in Humans Show a Theta Rhythmic Modulation of Auditory Nerve Activity by Selective Attention.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Article
- Testing the auditory steady-state response (ASSR) to 40-Hz and 27-Hz click trains in children with autism spectrum disorder and their first-degree biological relatives: A high-density electroencephalographic (EEG) study.bioRxiv : the preprint server for biology · 2025Article
- Experimental Study on the Effects of Cockpit Noise on Physiological Indicators of Pilots.Sensors (Basel, Switzerland) · 2025Article
- Salience-Dependent Disruption of Sustained Auditory Attention Can Be Inferred from Evoked Pupil Responses and Neural Tracking of Task-Irrelevant Sounds.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Auditory efferent suppression during alternate auditory attention in schizophrenia patients with auditory hallucinations.Scientific reports · 2025Article
- Neural Correlates of Perceptual Plasticity in the Auditory Midbrain and Thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Eye movements track prioritized auditory features in selective attention to natural speech.Nature communications · 2024Article
- Neural correlates of flexible sound perception in the auditory midbrain and thalamus.bioRxiv : the preprint server for biology · 2024Article
- Individual prediction tendencies do not generalize across modalities.Psychophysiology · 2024Article
- Detection of Spatially Localized Sounds Is Robust to Saccades and Concurrent Eye Movement-Related Eardrum Oscillations (EMREOs).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Neural speech tracking shifts from the syllabic to the modulation rate of speech as intelligibility decreases.Psychophysiology · 2023Article
- Early-Life Stress Impairs Perception and Neural Encoding of Rapid Signals in the Auditory Pathway.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- The corticofugal oscillatory modulation of the cochlear receptor during auditory and visual attention is preserved in tinnitus.Frontiers in neural circuits · 2023Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
The architecture of the efferent auditory system enables prioritization of strongly overlapping spatiotemporal cochlear activation patterns elicited by relevant and irrelevant inputs. So far, attempts at finding such attentional modulations of cochlear activity delivered indirect insights in humans or required direct recordings in animals. The extent to which spiral ganglion cells forming the human auditory nerve are sensitive to selective attention remains largely unknown. We investigated this question by testing the effects of attending to either the auditory or visual modality in human cochlear implant (CI) users (3 female, 13 male). Auditory nerve activity was directly recorded with standard CIs during a silent (anticipatory) cue-target interval. When attending the upcoming auditory input, ongoing auditory nerve activity within the theta range (5-8 Hz) was enhanced. Crucially, using the broadband signal (4-25 Hz), a classifier was even able to decode the attended modality from single-trial data. Follow-up analysis showed that the effect was not driven by a narrow frequency in particular. Using direct cochlear recordings from deaf individuals, our findings suggest that cochlear spiral ganglion cells are sensitive to top-down attentional modulations. Given the putatively broad hair-cell degeneration of these individuals, the effects are likely mediated by alternative efferent pathways compared with previous studies using otoacoustic emissions. Successful classification of single-trial data could additionally have a significant impact on future closed-loop CI developments that incorporate real-time optimization of CI parameters based on the current mental state of the user.
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