ArticleBMJ open2022
Danish validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ) and findings from a population health survey: a mixed-methods study.
Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06402409 (Workpackage 1), which is not on this map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Workpackage 1: Baseline Prevalence and Implications of Multimorbidity for the Management of Spinal Pain Workpackage 2: The Influence of Multimorbidity Treatment Burden on Long-term Prognosis of Individuals With Spinal Pain
Who cites it
17 citing papers in PubMed.
- Adaptation and psychometric validation of treatment burden questionnaire for caregivers of older adults with diabetes and dementia.Aging & mental health · 2026Article
- Development and validation of a Japanese version of the multimorbidity treatment burden questionnaire.Scientific reports · 2025Article
- Perceived treatment burden and health-related quality of life in association with healthcare utilisation among patients attending multiple outpatient clinics.Health and quality of life outcomes · 2025Article
- Measurement of treatment burden in patients with multimorbidity in the Netherlands: translation and validation of the Multimorbidity Treatment Burden Questionnaire (NL-MTBQ).Family practice · 2024Article
- Network of doctors for multimorbidity and diabetes - the NOMAD intervention: protocol for feasibility trial of multidisciplinary team conferences for people with diabetes and multimorbidity.Pilot and feasibility studies · 2024Article
- Social Disconnectedness in Individuals with Cardiovascular Disease: Associations with Health Literacy and Treatment Burden.International journal of behavioral medicine · 2024Article
- Further development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ).BMJ open · 2024Article
- Article
- Validation of the Lithuanian multimorbidity treatment burden questionnaire (MTBQ) and its association with primary care patient characteristics.The European journal of general practice · 2023Article
- Relationship between Treatment Burden, Health Literacy, and Medication Adherence in Older Adults Coping with Multiple Chronic Conditions.Medicina (Kaunas, Lithuania) · 2023Article
- Adaptation and validation of a German version of the Multimorbidity Treatment Burden Questionnaire.Health and quality of life outcomes · 2022Article
- Outpatients' perceptions of collaboration across clinics and health literacy among patients with diabetes and at least one comorbidity: A hospital-level cross-sectional study.Journal of multimorbidity and comorbidityArticle
- Development of the Short Treatment Burden Questionnaire (STBQ) including a Global Treatment Burden Question (GTBQ): Cognitive interviews with adults living with multimorbidity.Journal of multimorbidity and comorbidityArticle
- The Effect of Coordinating the Outpatient Treatment across Medical Specialities for Patients With Multimorbidity.International journal of integrated careArticle
- Multimorbidity patterns and their associations with patient-perceived treatment burden: A latent class analysis of 14,344 Danish adults.Journal of multimorbidity and comorbidityArticle
- Associations between treatment burden, socio-demographics, clinical factors and use of medicines in adults with polypharmacy: A cross-sectional study.Journal of multimorbidity and comorbidityArticle
- Validation of the Global Treatment Burden Question (GTBQ): A novel single-item measure for use in clinical and research settings.Journal of multimorbidity and comorbidityArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo validate the Danish Multimorbidity Treatment Burden Questionnaire (MTBQ) and obtain a population-based evaluation of treatment burden.
designMixed-methods.
settingDanish population-based survey.
participantsTranslation by professional translators and an expert group. The scale was tested by 13 407 participants (aged ≥25 years) in treatment. MEASURES: The 10-item MTBQ was translated into Danish using forward-backward translation and used in a large population health survey. A global MTBQ score was calculated and factor analysis and Cronbach's alpha assessed dimensional structure and internal consistency reliability, respectively. Spearman's rank correlations between global MTBQ scores and scores of self-rated health, health-related quality of life and the number of long-term conditions, respectively, assessed construct validity. MTBQ scores were grouped into four categories (no, low, medium, high burden) to assess interpretability and population-based evaluation of treatment burden.
resultsThe scale showed high internal consistency (α=0.87), positive skewness and large floor effects. Factor analysis supported a one-dimensional structure of the scale with a three-dimensional structure as a less parsimonious alternative. The MTBQ score was negatively associated with self-rated health (r
conclusionThe Danish MTBQ is a valid measure of treatment burden with good construct validity and high internal reliability. This is the first study to explore treatment burden at a population level and provides important evidence to policy makers and clinicians about sociodemographic groups at risk of higher treatment burden.
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