Evidence map›Paper›PMID 34980614›Full record

ArticleBMJ open2022

Effect of fertility health awareness strategies on fertility knowledge and childbearing in young married couples (FertStart): study protocol for an effectiveness-implementation hybrid type I multicentre three-arm parallel group open-label randomised clinical trial.

Sze Ling Chan, Julian Thumboo, Jacky Boivin, Seyed Ehsan Saffari, Shanqing Yin, Samantha Rachel Yeo, Jerry Kok Yen Chan, Kee Chong Ng, Ka-Hee Chua, Su Ling Yu

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04647136 (The Effect of Fertility Health Awareness Strategies on Fertility Knowledge and Childbearing in Young Married Couples), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04647136 nacompletednot on this map

The Effect of Fertility Health Awareness Strategies on Fertility Knowledge and Childbearing in Young Married Couples (FertStart)

TypeinterventionalSponsorSingapore General HospitalRan2015 to 2024Enrolled841ConditionsFertility Awareness, Childbearing IntentionsArmsFertility Health Screening, Fertility Awareness Tools
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Sze Ling ChanHealth Services Research Centre, Singhealth, Singapore.ORCID 0000-0003-4272-4595
Julian ThumbooDepartment of Rheumatology & Immunology, Singapore General Hospital, Singapore.
Jacky BoivinSchool of Psychology, Cardiff University, Cardiff, UK.
Seyed Ehsan SaffariCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore.
Shanqing YinChairman Medical Board Office, KK Women's and Children's Hospital, Singapore.
Samantha Rachel YeoDivision of Obstetrics & Gynaecology, KK Women's and Children's Hospital, Singapore.
Jerry Kok Yen ChanDepartment of Reproductive Medicine, KK Women's and Children's Hospital, Singapore.
Kee Chong NgChairman Medical Board Office, KK Women's and Children's Hospital, Singapore.
Ka-Hee ChuaDepartment of Reproductive Medicine, KK Women's and Children's Hospital, Singapore.
Su Ling YuDepartment of Obstetrics & Gynaecology, Singapore General Hospital, Singapore yu.su.ling@singhealth.com.sg yu.su.ling@singhealth.com.sg.
KK Women's and Children's Hospital · SGSingapore General Hospital · SGCardiff University · GBDuke-NUS Medical School · SGSingHealth · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBirth rates have been declining in many advanced societies including Singapore. We designed two interventions with vastly different resource requirements, which include fertility education, personalised fertility information and a behavioural change component targeting modifiable psychological constructs to modify fertility awareness and childbearing intentions. We aim to evaluate the effect of these two interventions on knowledge, attitudes and practice around childbearing compared with a control group among young married couples in Singapore and understand the implementation factors in the setting of an effectiveness-implementation hybrid type 1 three-arm randomised trial. METHODS AND ANALYSIS: We will randomise 1200 young married couples to no intervention (control), Fertility Health Screening group (FHS) or Fertility Awareness Tools (FAT) in a 7:5:5 ratio. Couples in FHS will undergo an anti-Mullerian hormone test and semen analysis, a doctor's consultation to explain the results and standardised reproductive counselling by a trained nurse. Couples in FAT will watch a standardised video, complete an adapted fertility status awareness (FertiSTAT) tool and receive an educational brochure. The attitudes, fertility knowledge and efforts to achieve pregnancy of all couples will be assessed at baseline and 6 months post-randomisation. Birth statistics will be tracked using administrative records at 2 and 3 years. The primary outcome is the change in the woman's self-reported intended age at first birth between baseline and 6 months post-randomisation. In addition, implementation outcomes and cost-effectiveness of the two interventions will be assessed. ETHICS AND DISSEMINATION: This study has been reviewed and approved by the Centralized Institutional Review Board of SingHealth (2019/2095). Study results will be reported to the study funder and there are plans to disseminate them in scientific conferences and publications, where authorship will be determined by the International Committee of Medical Journal Editors guidelines. TRIAL REGISTRATION NUMBER: NCT04647136; ClinicalTrails.gov Identifier.

Indexed as

FertilityResearch DesignBirth RateCounselingFamily Planning ServicesFemaleHumansInfantMulticenter Studies as TopicPregnancyRandomized Controlled Trials as Topiceducation & training (see medical education & training)gynaecologyreproductive medicinesubfertility

Identifiers

PMID34980614
PMCPMC8724708
OpenAlexW4205287346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.