Evidence map›Paper›PMID 34980564›Full record

ReviewJournal of cardiac failure2022

Physiology and Clinical Utility of HeartMate Pump Parameters.

Mark N Belkin, Viktoriya Kagan, Colleen Labuhn, Sean P Pinney, Jonathan Grinstein

Abstract readReview
In one paragraph

Review in Journal of cardiac failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Abrupt flow decline as the initial indicator of early HeartMate 3 pump thrombosis.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026
    Article
  4. Article
  5. The impact of position changes of the inflow cannula in LVAD patients.Turk gogus kalp damar cerrahisi dergisi · 2026
    Article
  6. Management of Dialysis for Patients Receiving Mechanical Circulatory Support.Journal of the American Society of Nephrology : JASN · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Successful management of HeartMate 3 in a patient with arrhythmogenic right ventricular cardiomyopathy.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2024
    Article
  18. Article
  19. Aortic valve disorders and left ventricular assist devices.Frontiers in cardiovascular medicine · 2023
    Review
  20. A Holistic View of Advanced Heart Failure.Life (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mark N BelkinUniversity of Chicago Medicine, Section of Cardiology, Chicago, Illinois.
Viktoriya KaganUniversity of Chicago Medicine, Section of Cardiac Surgery, Chicago, Illinois.
Colleen LabuhnUniversity of Chicago Medicine, Section of Cardiac Surgery, Chicago, Illinois.
Sean P PinneyUniversity of Chicago Medicine, Section of Cardiology, Chicago, Illinois.
Jonathan GrinsteinUniversity of Chicago Medicine, Section of Cardiology, Chicago, Illinois. Electronic address: jgrinstein@medicine.bsd.uchicago.edu.

Funding

MULTIDISCIPLINARY CARDIAC SCIENCEST32HL007381 · NHLBI · UNIVERSITY OF CHICAGO · PI JEANNE M DECARA, Yoav Gilad · 1985 to 2026
$12.5M
NHLBI NIH HHS T32 HL007381
6 · The paper itself

Abstract

The HeartMate 3 left ventricular assist device (LVAD) is now the only centrifugal pump intended for durable support being actively manufactured and implanted for adults in the United States. The changes in preload and afterload that accompany common clinical scenarios experienced by patients with an LVAD will cause specific changes to the LVAD pump parameters, namely, the pump power, pulsatility index, and flow. Appropriate care of this unique, and growing, population requires a full understanding of these variables as well as the underlying physiologic principles governing their derivation. The aim of this review is to focus on the updated functionality of the HeartMate 3, specifically in comparison to the HeartMate II, as well as the application of pump parameter interpretation to common clinical scenarios.

Indexed as

Heart-Assist DevicesHeart FailureAdultHumansHeartMateLeft ventricular assist devicepulsatility indexpump parameters

Identifiers

PMID34980564
PMCPMC9106934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.