Evidence map›Paper›PMID 34980281›Full record

ArticleInternational journal of retina and vitreous2022

Diabetic retinopathy classification for supervised machine learning algorithms.

Luis Filipe Nakayama, Lucas Zago Ribeiro, Mariana Batista Gonçalves, Daniel A Ferraz, Helen Nazareth Veloso Dos Santos, Fernando Korn Malerbi, Paulo Henrique Morales, Mauricio Maia, Caio Vinicius Saito Regatieri, Rubens Belfort Mattos

Abstract readLetter
In one paragraph

Article in International journal of retina and vitreous, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Artificial intelligence in diabetic retinopathy: from automated screening to risk-stratified care.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luis Filipe NakayamaPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil. nakayama.luis@gmail.com.ORCID http://orcid.org/0000-0002-6847-6748
Lucas Zago RibeiroPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil.
Mariana Batista GonçalvesPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil.
Daniel A FerrazPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil.
Helen Nazareth Veloso Dos SantosPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil.
Fernando Korn MalerbiPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil.
Paulo Henrique MoralesPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil.
Mauricio MaiaPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil.
Caio Vinicius Saito RegatieriPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil.
Rubens Belfort MattosPhysician, Department of Ophthalmology, Universidade Federal de São Paulo - EPM, Botucatu Street, 821, Vila Clementino, São Paulo, SP, 04023-062, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence and automated technology were first reported more than 70 years ago and nowadays provide unprecedented diagnostic accuracy, screening capacity, risk stratification, and workflow optimization. Diabetic retinopathy is an important cause of preventable blindness worldwide, and artificial intelligence technology provides precocious diagnosis, monitoring, and guide treatment. High-quality exams are fundamental in supervised artificial intelligence algorithms, but the lack of ground truth standards in retinal exams datasets is a problem. MAIN BODY: In this article, ETDRS, NHS, ICDR, SDGS diabetic retinopathy grading, and manual annotation are described and compared in publicly available datasets. The various DR labeling systems generate a fundamental problem for AI datasets. Possible solutions are standardization of DR classification and direct retinal-finding identifications.

conclusionReliable labeling methods also need to be considered in datasets with more trustworthy labeling.

Indexed as

Artificial intelligenceDatasetsDiabetic retinopathy classifications

Identifiers

PMID34980281
PMCPMC8722080

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.