Evidence map›Paper›PMID 34980278›Full record

ArticleBMC nutrition2022

Intake of n-3 LCPUFA and trans-fatty acids is unrelated to development in body mass index and body fat among children.

Xuan Ren, Sofus Christian Larsen, Lotte Lauritzen, Jeanett Friis Rohde, Lars Bo Andersen, Anna Bugge, Britt Wang Jensen, Ina Olmer Specht, Berit Lilienthal Heitmann

Open access · goldAbstract read
In one paragraph

Article in BMC nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Xuan RenResearch Unit for Dietary Studies at The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Sofus Christian LarsenResearch Unit for Dietary Studies at The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Lotte LauritzenDepartment of Nutrition, Exercise and Sports, Paediatric and International Nutrition, University of Copenhagen, Copenhagen, Denmark.
Jeanett Friis RohdeResearch Unit for Dietary Studies at The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Lars Bo AndersenDepartment of Education, Arts and Sport, Western Norway University of Applied Sciences, Sogndal, Norway.
Anna BuggeDepartment of Midwifery, Physiotherapy, Occupational Therapy and Psychomotor Therapy, University College Copenhagen, Copenhagen, Denmark.
Britt Wang JensenCenter for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Ina Olmer SpechtResearch Unit for Dietary Studies at The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Berit Lilienthal HeitmannResearch Unit for Dietary Studies at The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Frederiksberg Hospital · DKUniversity College Copenhagen · DKUniversity of Copenhagen · DKWestern Norway University of Applied Sciences · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of children and adolescents with obesity has increased worldwide. Some studies have found an increase in the intake of n-3 long-chain polyunsaturated fatty acid (LCPUFA) to be beneficial for weight and obesity status. The objectives of this study were to examine if intake of trans-fatty acids (TFA) and n-3 LCPUFA at school start was associated with weight and body fat development in the following 3 and 7 years, and if substituting other fats for n-3 LCPUFA in regression models influenced weight and body fat development.

methodsA total of 285 children (boys:130, girls:155) were included in this study. Weight, height and skinfold thickness (SF) of children were measured at age 6, 9 and 13 years by trained research personnel. Multivariate linear regression models were used to investigate the associations between n-3 LCPUFA or TFA intake and subsequent changes in body mass index (BMI) or SF. To investigate substitution effects, we constructed regression models including information on n-3 LCPUFA and all other energy given components of the diet, except for the nutrient to be substituted (all other fats and specific subgroups; saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs) and other polyunsaturated fatty acids (PUFAs)).

resultsNo significant associations were observed between intake of TFA or n-3 LCPUFA and changes in BMI and SF. Also, results from regression analysis showed substituting other fats for n-3 LCPUFA did not associate with BMI or SF development.

conclusionThe lack of associations between n-3 LCPUFA and TFA and adiposity suggests that fat composition in the diet does not play a major role in obesity development among school-aged children.

Indexed as

BMIbody fatchildrenfatty acidssubstitution

Identifiers

PMID34980278
PMCPMC8722340
OpenAlexW4206251400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.