Evidence map›Paper›PMID 34980179›Full record

ArticleSubstance abuse treatment, prevention, and policy2022

Outcomes from the medication assisted treatment pilot program for adults with opioid use disorders in rural Colorado.

Claudia R Amura, Tanya R Sorrell, Mary Weber, Andrea Alvarez, Nancy Beste, Ursula Hollins, Paul F Cook

Abstract read
In one paragraph

Article in Substance abuse treatment, prevention, and policy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Claudia R AmuraUniversity of Colorado College of Nursing, 13120 E. 19th Ave, Aurora, CO, 80045, USA. claudia.amura@cuanschutz.edu.ORCID 0000-0003-2825-2659
Tanya R SorrellUniversity of Colorado College of Nursing, 13120 E. 19th Ave, Aurora, CO, 80045, USA.
Mary WeberUniversity of Colorado College of Nursing, 13120 E. 19th Ave, Aurora, CO, 80045, USA.
Andrea AlvarezHealth Solutions Inc, 41 Montebello Rd., Pueblo, CO, 81001, USA.
Nancy BesteMountain Medical: Road to Recovery, PO Box 773705, Steamboat Springs, CO, 80477, USA.
Ursula HollinsColorado Treatment Services, 511 W. 29th St. Pueblo, CO 91008 USA Colorado Treatment Services, Pueblo, CO, 91008, USA.
Paul F CookUniversity of Colorado College of Nursing, 13120 E. 19th Ave, Aurora, CO, 80045, USA.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
NCATS NIH HHS UL1 TR002535
6 · The paper itself

Abstract

backgroundAs Colorado ranked among the top nationally in non-medical use of opioids, a pilot medication for opioid use disorder (MOUD) program was developed to increase the number of NPs and PAs providing MOUD in order to bring this evidence- based treatment to 2 counties showing disproportionally high opioid overdose deaths. Over the first 18 months, the MOUD Pilot Program led to 15 new health care providers receiving MOUD waiver training and 1005 patients receiving MOUD from the 3 participating organizations. Here we evaluate patient centered clinical and functional outcomes of the pilot MOUD program implemented in 2 rural counties severely affected by the opioid crisis.

methodsUnder state-funded law (Colorado Senate Bill 17-074), three rural agencies submitted de-identified patient-level data at baseline (N = 1005) and after 6 months of treatment (N = 190, 25%) between December 2017 and January 2020. The Addiction Severity Index, PhQ9 and GAD-7 with McNemar-Bowker, and Wilcoxon Signed Rank tests analysis were used to measure patient outcomes across after participation in the program. .

resultsPatients in treatment reported using less heroin (52.1% vs 20.4%), opioids (22.3% vs 11.0%), and alcohol (28.6% vs 13.1%, all P < 0.01). Patients reported improved health (53.4% vs. 68.2%, P = 0.04), less frequency of disability (8.69 vs. 6.51, P = 0.02), symptoms (29.8% vs 21.3%), pain (67.5% to 53.6), worry (45.3% vs 62.3%), anxiety (49.7% vs 23.2%), depression (54.1% vs 23.3%, all P < 0.02) after treatment.

conclusionsThis study shows decreased substance use, improved physical and mental health, and reduced symptoms after 6 months of MOUD. Although more research on retention and long-term effects is needed, data shows improved health outcomes after 6 months of MOUD. Lessons learned from implementing this pilot program informed program expansion into other rural areas in need to address some of Colorado' major public health crises.

Indexed as

BuprenorphineOpioid-Related DisordersAdultAnalgesics, OpioidColoradoHumansPilot ProjectsAnalgesics, OpioidBuprenorphineCommunity settingsMedication-assisted treatment for opioid use disorderPainPatient centered outcomesRural

Identifiers

PMID34980179
PMCPMC8722086

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.