ArticleBMC veterinary research2022
18F-FDG PET/CT image findings of a dog with adrenocortical carcinoma.
Article in BMC veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Case Report: Multimodality imaging features and serial metabolic changes onFrontiers in veterinary science · 2026Article
- Feasibility ofVeterinary medicine and science · 2025Article
- Modern applications of positron emission tomography/computed tomography (PET/CT) imaging in veterinary oncology - A brief overview.The Canadian veterinary journal = La revue veterinaire canadienne · 2024Article
- Case report: Evaluation of cutaneous squamous cell carcinoma metastasized to lymph nodes usingFrontiers in veterinary science · 2024Article
- Case report: Successful medical management of adrenocortical carcinoma with metastasis in a Maltese dog.Frontiers in veterinary science · 2023Article
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8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundIn human medicine, 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) has been used to differentiate between benign and malignant adrenal tumors and to identify metastases. However, canine adrenocortical carcinomas identified by 18F-FDG PET/computed tomography (CT) have not been reported. CASE PRESENTATION: A 13-year-old, castrated male, Cocker Spaniel dog with severe systolic hypertension exhibited an adrenal mass approximately 3.6 cm in diameter on ultrasonography. There was no evidence of pulmonary metastasis or vascular invasion on thoracic radiography and abdominal ultrasonography, respectively. 18F-FDG PET/CT was performed to identify the characteristics of the adrenal mass and the state of metastasis. One hour after injection of 5.46 MBq/kg 18F-FDG intravenously, the peripheral region of the adrenal mass visually revealed an increased 18F-FDG uptake, which was higher than that of the liver, and the central region of the mass exhibited necrosis. The maximal standardized uptake value (SUV) of the adrenal mass was 3.24; and relative SUV, calculated by dividing the maximal SUV of the adrenal tumor by the mean SUV of the normal liver, was 5.23. Adrenocortical carcinoma was tentatively diagnosed and surgical adrenalectomy was performed. Histopathologic examination of the resected adrenal mass revealed the characteristics of an adrenocortical carcinoma. After adrenalectomy, systolic blood pressure reduced to below 150 mmHg without any medication.
conclusionThis is the first case report of 18F-FDG PET/CT findings in a dog with suspected adrenocortical carcinoma and may provide valuable diagnostic information for adrenocortical carcinoma in dogs.
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