Evidence map›Paper›PMID 34980057›Full record

ArticleBMC pediatrics2022

Clinical study of recurrent mild encephalitis/encephalopathy with a reversible splenial lesion in two cases.

Jiao Xue, Chongfeng Duan, Guizhi Xu, Ying Zhang, Zhenfeng Song, Zhi Yi, Chengqing Yang, Fei Li, Kaixuan Liu, Hongshan Zhao and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Frontiers in genetics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jiao XueDepartment of Pediatric Neurology, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Chongfeng DuanDepartment of Radiology, the Affiliated Hospital of Qingdao University, Qingdao, No. 1677 Wutaishan Road, Qingdao, Shandong, 266000, PR China.
Guizhi XuDepartment of Radiology, Zhucheng People Hospital, Weifang, 262200, Shandong, China.
Ying ZhangDepartment of Pediatric Neurology, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Zhenfeng SongDepartment of Pediatric Neurology, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Zhi YiDepartment of Pediatric Neurology, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Chengqing YangDepartment of Pediatric Neurology, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Fei LiDepartment of Pediatric Neurology, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Kaixuan LiuDepartment of Pediatric Neurology, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Hongshan ZhaoDepartment of Anesthesiology, the Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.
Xuejun LiuDepartment of Radiology, the Affiliated Hospital of Qingdao University, Qingdao, No. 1677 Wutaishan Road, Qingdao, Shandong, 266000, PR China. bncz@sina.com.
Affiliated Hospital of Qingdao University · CNQingdao University · CNZoucheng People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMild encephalitis/encephalopathy with a reversible splenial lesion (MERS) has been reported worldwidely. However, the data about recurrent cases is limited. We aimed to analyze the clinical and radiographic features of recurrent MERS, and its possible mechanisms. CASE PRESENTATION: Two patients with clinically recurrent MERS were reported here, exhibiting neurological symptoms such as limbs weakness and numbness, stand/walk unsteadily, slurred speech and irritability, and typical lesions in the corpus callosum and white matter. One of them experienced another four episodes with a similar clinical course and magnetic resonance imaging findings over a period of 10 years. The Na levels in the present two patients were normal. DISCUSSION AND

conclusionCombined with the patients reported previously, recurrence could be seen in both MERS type 1 and type 2 patients, from two to multiple times, with the latter possibly more common. It suggested that some genetic factors might be involved in MERS, especially for MERS type 2 or familial MERS.

Indexed as

Brain DiseasesEncephalitisCorpus CallosumHumansMagnetic Resonance ImagingChildMERSRecurrent

Identifiers

PMID34980057
PMCPMC8722321
OpenAlexW4206555514

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.