Evidence map›Paper›PMID 34979971›Full record

ArticleBMC nephrology2022

Prevalence, correlates and in-hospital outcomes of kidney dysfunction in hospitalized patients with heart failure in Buea-Cameroon.

Ahmadou Musa Jingi, Clovis Nkoke, Jean Jacques Noubiap, Denis Teuwafeu, Alex T Mambap, Cyrille Nkouonlack, Ronald Gobina, Debimeh Njume, Anastase Dzudie, Gloria Ashuntantang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Advancing Guideline-Directed Medical Therapy in Heart Failure: Overcoming Challenges and Maximizing Benefits.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Ahmadou Musa JingiFaculty of Health Sciences, University of Bamenda, Bamenda, Cameroon.
Clovis NkokeBuea Regional Hospital, Buea, Cameroon. cnkoke@yahoo.com.
Jean Jacques NoubiapCenter for Heart Rhythm Disorders, University of Adelaide, Adelaide, SA, Australia.
Denis TeuwafeuBuea Regional Hospital, Buea, Cameroon.
Alex T MambapFaculty of Health Sciences, University of Bamenda, Bamenda, Cameroon.
Cyrille NkouonlackBuea Regional Hospital, Buea, Cameroon.
Ronald GobinaBuea Regional Hospital, Buea, Cameroon.
Debimeh NjumeFaculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaoundé, Cameroon.
Anastase DzudieClinical Research Education, Networking and Consultancy (CRENC), Douala, Cameroon.
Gloria AshuntantangFaculty of Health Sciences, University of Bamenda, Bamenda, Cameroon.
University of Buea · CMUniversity of Bamenda · CMUniversité de Yaoundé I · CMUniversity of Adelaide · AUUniversity of Douala · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidney dysfunction is common in patients with heart failure (HF) and has been associated with poor outcomes. This study aimed to determine the prevalence, correlates, and prognosis of kidney dysfunction in patients with HF in Cameroon, an understudied population.

methodsWe conducted a cross-sectional study in consecutive patients hospitalized with HF between June 2016 and November 2017 in the Buea Regional Hospital, Cameroon. Kidney dysfunction was defined as an estimated glomerular filtration rate < 60 ml/min/1.73m

resultsSeventy four patients (86.1% of those eligible) were included. Their median age was 60 (interquartile range: 44-72) years and 46.0% (n = 34) were males. Half of patients (n = 37) had kidney dysfunction. Correlates of kidney dysfunction included previous diagnosis of HF (adjusted odds ratio [aOR]4.3, 95% CI: 1.1-17.5) and left ventricular hypertrophy (aOR3.4, 95% CI: 1.1-9.9). Thirty-six (48.9%) had prolonged hospital stay, and seven (9.5%) patients died in hospital. Kidney dysfunction was not associated with in-hospital death (aOR 0.4, 95% CI: 0.1-2) nor prolonged hospital stay (aOR 2.04, 0.8-5.3). In sensitivity analysis (excluding racial consideration), factors associated with Kidney dysfunction in HF were; anemia (aOR: 3.0, 95% CI: 1.1-8.5), chronic heart failure (aOR: 4.7, 95% CI: 0.9-24.6), heart rate on admission < 90 bpm (aOR: 3.4, 95% CI: 1.1-9.1), left atrial dilation (aOR: 3.2, 95% CI: 1.04-10), and hypertensive heart disease (aOR: 3.1, 95% CI: 1.2-8.4). Kidney dysfunction in HF was associated with hospital stay > 7 days (OR: 2.6, 95% CI: 1-6.8).

conclusionModerate-to-severe kidney dysfunction was seen in half of the patients hospitalized with HF in our setting, and this was associated with a previous diagnosis of HF and left ventricular hypertrophy. Kidney dysfunction might not be the main driver of poor HF outcomes in this population. In sensitivity analysis, this was associated with anemia, chronic heart failure, heart rate on admission less than 90 bpm, left atrial dilatation, and hypertensive heart disease. Kidney dysfunction was associated with hospital stay > 7 days.

Indexed as

AdultAgedAged, 80 and overCameroonCross-Sectional StudiesFemaleGlomerular Filtration RateHeart FailureHospital MortalityHumansHypertrophy, Left VentricularKidneyLength of StayMaleMiddle AgedPrevalenceCameroonHeart failureKidney dysfunctionMortalityOutcomeSub-Saharan Africa

Identifiers

PMID34979971
PMCPMC8722319
OpenAlexW4206023131

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.