Evidence map›Paper›PMID 34979592›Full record

ReviewJournal of child psychology and psychiatry, and allied disciplines2022

Annual Research Review: The contributions of the RDoC research framework on understanding the neurodevelopmental origins, progression and treatment of mental illnesses.

Jennifer Pacheco, Marjorie A Garvey, Christopher S Sarampote, Elan D Cohen, Eric R Murphy, Stacia R Friedman-Hill

Erratum issuedAbstract readReview
In one paragraph

Review in Journal of child psychology and psychiatry, and allied disciplines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  8. Child and adolescent psychiatry: challenges, solutions, opportunities, and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jennifer PachecoDivision of Translational Research, National Institute of Mental Health, Bethesda, MD, USA.
Marjorie A GarveyDivision of Translational Research, National Institute of Mental Health, Bethesda, MD, USA.
Christopher S SarampoteDivision of Translational Research, National Institute of Mental Health, Bethesda, MD, USA.
Elan D CohenOffice of Science Policy, Planning, and Communications, National Institute of Mental Health, Bethesda, MD, USA.
Eric R MurphyDivision of Translational Research, National Institute of Mental Health, Bethesda, MD, USA.
Stacia R Friedman-HillDivision of Translational Research, National Institute of Mental Health, Bethesda, MD, USA.

Funding

HSRD VA PPO 16-135Intramural NIH HHS Z99 MH999999
6 · The paper itself

Abstract

The National Institute of Mental Health (NIMH) proposed the Research Domain Criteria (RDoC) initiative as an alternate way to organize research of mental illnesses, by looking at dimensions of functioning rather than being tied to categorical diagnoses. This paper briefly discusses the motivation for and organization of RDoC, and then explores the NIMH portfolio and recent work to monitor the utility and progress that RDoC has afforded developmental research. To examine how RDoC has influenced the NIMH developmental research portfolio over the last decade, we employed a natural language processing algorithm to identify the number of developmental science grants classified as incorporating an RDoC approach. Additional portfolio analyses examine temporal trends in funded RDoC-relevant grants, publications and citations, and research training opportunities. Reflecting on how RDoC has influenced the focus of grant applications, we highlight examples from research on Attention-Deficit Hyperactivity Disorder (ADHD), childhood irritability, and Autism Spectrum Disorder (ASD). Lastly, we consider how the dimensional and transdiagnostic approaches emphasized in RDoC have facilitated research on personalized intervention for heterogeneous disorders and preventive/early interventions targeting emergent or subthreshold psychopathology.

Indexed as

Attention Deficit Disorder with HyperactivityAutism Spectrum DisorderMental DisordersChildHumansNational Institute of Mental Health (U.S.)PsychopathologyUnited StatesADHDautism spectrum disordersdevelopmentintervention

Identifiers

PMID34979592
PMCPMC8940667

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.