Evidence map›Paper›PMID 34979299›Full record

ArticleJournal de mycologie medicale2022

Surgical & medical management of ROCM (Rhino-orbito-cerebral mucormycosis) epidemic in COVID-19 era and its outcomes - a tertiary care center experience.

Kapil Soni, Aparna Das, Vidhu Sharma, Amit Goyal, Bikram Choudhury, Ankita Chugh, Deepak Kumar, Taruna Yadav, Vidhi Jain, Ashwini Agarwal and 6 more

Open access · greenAbstract read
In one paragraph

Article in Journal de mycologie medicale, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Correlation of Interleukin-6 Levels With Disease Severity in Rhino-Orbito-Cerebral Mucormycosis: A Prospective Study.Journal of rhinology : official journal of the Korean Rhinologic Society · 2025
    Article
  2. Breaking New Ground: Novel Intralesional Amphotericin B for Mucormycosis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  3. Article
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  5. WHO BREF Quality of Life Score as a Prognostic Indicator of Survival in Patients recovered from COVID-19 Associated Rhino-Orbito-Cerebral Mucormycosis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  6. Article
  7. Outcome of Total Surgical Debridement of Covid Associated Rhino-Orbito-Cerebral Mucormycosis Based on a New Surgical Staging System: A Cohort Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Kapil SoniDepartment of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Aparna DasDepartment of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Vidhu SharmaDepartment of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Amit GoyalDepartment of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India. Electronic address: meetugoyal@yahoo.com.
Bikram ChoudhuryDepartment of Otorhinolaryngology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Ankita ChughDepartment of Dentistry, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Deepak KumarDepartment of General Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Taruna YadavDepartment of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Vidhi JainDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Ashwini AgarwalDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Mayank GargDepartment of Neurosurgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Kavita BhatnagarDepartment of Ophthalmology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Poonam ElhenceDepartment of Pathology and Lab Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Pradeep Kumar BhatiaDepartment of Anesthesiology and Critical Care, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Mahendra Kumar GargDepartment of General Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
Sanjeev MisraDepartment of Surgical Oncology, All India Institute of Medical Sciences, Jodhpur, Rajasthan 342005, India.
All India Institute of Medical Sciences Jodhpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the outcome of patients with ROCM (Rhino-orbito-cerebral mucormycosis) following their medical and surgical management. MATERIALS AND

methodsIt is a prognostic study based in a tertiary care center in North-Western India. Patients who developed ROCM post COVID-19 infection from 1st September 2020 to 30th June 2021 were included in this study. Surgical debridement and administration of antifungal therapy was done for the post-COVID-19 ROCM patients. Disease progression and survival was studied up to 5 months of follow-up in the second wave.

resultsA total of 145 ROCM patients were included. The mean age at presentation, male: female ratio was 48.2 years and 2:1 respectively. As per our proposed new staging system and treatment strategy, the majority of patients belonged to stage II (31.72%) and stage III (31.03%). On a follow-up period of 5 months, 26 (18%) patients have lost their life and rest of the patients are on strict follow-up.

conclusionROCM is an extremely aggressive fungal infection which rapidly became an epidemic following the COVID-19 pandemic. The diverse and unique presentation led us to evolve a new strategy to classify and manage these patients.

Indexed as

COVID-19Eye Infections, FungalMucormycosisOrbital DiseasesAntifungal AgentsFemaleHumansMalePandemicsSARS-CoV-2Tertiary Care CentersAntifungal AgentsAmphotericinCOVID-19OutcomeROCM (rhino-orbito-cerebral mucormycosis)Staging protocolTreatment

Identifiers

PMID34979299
PMCPMC8709922
OpenAlexW4200625097

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.