ArticleThe Journal of infectious diseases2022
Lung Function Decline in Relation to COVID-19 in the General Population: A Matched Cohort Study With Prepandemic Assessment of Lung Function.
Article in The Journal of infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Recovery of lung function during the first year after COVID-19: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Long-term impact of SARS-CoV-2 infection on cardiorespiratory fitness: a meta-analysis.Frontiers in public health · 2023Pooled it
- Impact of SARS-CoV-2 Infection on Pulmonary Function in the PURE-Colombia Cohort: A Comparative Analysis with Pre-COVID Values and Non-COVID-19 Controls.Journal of clinical medicine · 2026Article
- Lung Function Impairment after Mild SARS-CoV-2 Infection in Previously Healthy Individuals.Respiration; international review of thoracic diseases · 2026Article
- SARS-CoV-2 reinfection in interstitial lung disease patients and its association with clinical deterioration: a two-year prospective cohort study.BMC infectious diseases · 2025Article
- Scars from the pandemic: understanding post-COVID-19 interstitial lung disease.Breathe (Sheffield, England) · 2025Review
- A comparison of pulmonary function pre and post mild SARS-CoV-2 infection among healthy adults.BMC pulmonary medicine · 2025Observational
- Effect of Continuous Positive Airway Pressure (CPAP) Mode on Lung Function, Exercise Tolerance, Vital Signs, and Dyspnea After Acute SARS-CoV-2 Infection.Clinics and practice · 2025Article
- Post-discharge spirometry evaluation in patients recovering from moderate-to-critical COVID-19: a cross-sectional study.Scientific reports · 2024Article
- Lung-function trajectories in COVID-19 survivors after discharge: A two-year longitudinal cohort study.EClinicalMedicine · 2022Article
- Lung Abnormalities in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: An Analysis of Paired Computed Tomography Scans Before and After Infection.Open forum infectious diseases · 2022Article
- Restrictive spirometry versus restrictive lung function using the GLI reference values.Clinical physiology and functional imaging · 2022Article
- Lung Function After Coronavirus Disease 2019: Some Answers, More Questions.The Journal of infectious diseases · 2022Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo quantify the potential decline in dynamic lung volumes following coronavirus disease 2019 (COVID-19) in the general population.
methodsA prospective matched cohort study of adult Copenhagen General Population Study (CGPS) participants with a prepandemic spirometry available. CGPS individuals with positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) test performed repeat spirometry, a questionnaire regarding respiratory symptoms, and diffusing capacity test for carbon monoxide. A matched uninfected CGPS control sample was used, and simple regression and linear mixed effect models were computed to study lung function decline.
resultsA total of 606 individuals were included; 92/107 (85.9%) with positive SARS-CoV-2 PCR test experienced coronavirus disease 2019 (COVID-19) symptoms and 12 (11.2%) were hospitalized. Spirometry was performed at median 5.6 months (interquartile range, 3.9-12.8) after positive SARS-CoV-2 PCR test. COVID-19 was associated with adjusted 7.3 mL (95% confidence interval [CI], .3-14.3) and 22.6 mL (95% CI, 13.1-32.0) steeper decline in annual forced expiratory volume in first second (FEV1) and FVC or total 113.8 and 301.3 mL lower FEV1 and FVC from baseline to follow-up. Results were robust in analyses restricted to individuals not requiring hospitalization.
conclusionsCOVID-19-related declines of dynamic lung volume in the general population not requiring hospitalization were small but measurable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.