Evidence map›Paper›PMID 34978926›Full record

ArticleInfection and immunity2022

Tsuyoshi Miki, Yusuke Hoshino, Naoki Sudo, Masahiro Ito, Takeshi Haneda, Nobuhiko Okada

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Microbiology (Reading, England) · 2026
    Article
  2. Article
  3. Article
  4. Outer membrane barrier impairment byMicrobiology (Reading, England) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Role of adherent invasiveWorld journal of clinical cases · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tsuyoshi MikiDepartment of Microbiology, School of Pharmacy, Kitasato University, Tokyo, Japan.ORCID 0000-0003-3563-2991
Yusuke HoshinoDepartment of Microbiology, School of Pharmacy, Kitasato University, Tokyo, Japan.
Naoki SudoDepartment of Microbiology, School of Pharmacy, Kitasato University, Tokyo, Japan.
Masahiro ItoDepartment of Microbiology, School of Pharmacy, Kitasato University, Tokyo, Japan.
Takeshi HanedaDepartment of Microbiology, School of Pharmacy, Kitasato University, Tokyo, Japan.
Nobuhiko OkadaDepartment of Microbiology, School of Pharmacy, Kitasato University, Tokyo, Japan.
Kitasato University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adherent-invasive Escherichia coli (AIEC) is involved in onset and/or exacerbation of Crohn's disease (CD). AIEC adapts to the gut environment by altering gene expression programs, leading to successful gut-lumen colonization. However, the underlying mechanism of gut colonization is still far from clarified. Here, we show the role of UvrY, a response regulator of bacterial two-component signal transduction systems, in AIEC gut colonization. An AIEC mutant lacking the

Indexed as

Crohn DiseaseEscherichia coli InfectionsAcetatesAnimalsBacterial AdhesionEpithelial CellsEscherichia coliFimbriae, BacterialIntestinal MucosaMiceAcetatesacetateAIECgut colonizationtype 1 fimbriaeUvrY

Identifiers

PMID34978926
PMCPMC8929387
OpenAlexW4206663255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.