Evidence map›Paper›PMID 34978748›Full record

Trial reportTropical medicine & international health : TM & IH2022

Person-centred care and short oral treatment for rifampicin-resistant tuberculosis improve retention in care in Kandahar, Afghanistan.

Anita Mesic, Sadiqullah Ishaq, Waliullah H Khan, Atiqullah Mureed, Htay Thet Mar, Ei Ei Khaing, Elkin Bermudez-Aza, Letitia Rose, Lutgarde Lynen, Mohammad Khaled Seddiq and 3 more

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Tropical medicine & international health : TM & IH, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Anita MesicMédecins Sans Frontières, Amsterdam, The Netherlands.
Sadiqullah IshaqMédecins Sans Frontières, Kabul, Afghanistan.
Waliullah H KhanMédecins Sans Frontières, Kabul, Afghanistan.
Atiqullah MureedMédecins Sans Frontières, Kandahar, Afghanistan.
Htay Thet MarMédecins Sans Frontières, Kandahar, Afghanistan.
Ei Ei KhaingMédecins Sans Frontières, Kandahar, Afghanistan.
Elkin Bermudez-AzaMédecins Sans Frontières, Amsterdam, The Netherlands.
Letitia RoseMédecins Sans Frontières, Kabul, Afghanistan.
Lutgarde LynenInstitute of Tropical Medicine Antwerp, Antwerp, Belgium.
Mohammad Khaled SeddiqNational Tuberculosis Control Programme, Ministry of Public Health, Kabul, Afghanistan.
Hashim Khan AmirzadaNational Tuberculosis Control Programme, Ministry of Public Health, Kabul, Afghanistan.
Kees KeusMédecins Sans Frontières, Amsterdam, The Netherlands.
Tom DecrooInstitute of Tropical Medicine Antwerp, Antwerp, Belgium.
Kandahar University · AFMédecins Sans Frontières · NLInstituut voor Tropische Geneeskunde · BEMinistry of Public Health · AF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the effect of adaptations to a person-centred care with short oral regimens on retention in care for rifampicin-resistant TB (RR-TB) in Kandahar province, Afghanistan.

methodsThe study included people with RR-TB registered in the programme between 01 October 2016 and 18 April 2021. From 19 November 2019, the programme implemented a trial investigating the safety and effectiveness of short oral RR-TB regimens. During the trial, person-centred care was adapted. We included the data from people living with RR-TB treated in the period before and after the care model was adapted and applied Kaplan-Meier statistics to compare rates of retention in care.

resultsOf 236 patients registered in the RR-TB programme, 146 (61.9%) were registered before and 90 (38.1%) after the model of care was adapted. Before adaptations enhancing person-centred care, pre-treatment attrition was 23.3% (n = 34/146), whilst under the adapted care model it was 5.6% (n = 5/90). Attrition on treatment was 22.3% (n = 25/112) before adaptations, whilst during the study period none of the participants were lost-to-follow-up on treatment and 3.3% died (n = 3/90).

conclusionsAs person-centred care delivery and treatment regimens were adapted to better fit-specific contextual challenges and the needs of the target population, retention in care improved amongst people with RR-TB in Kandahar, Afghanistan.

Indexed as

Patient-Centered CareAdolescentAdultAfghanistanAntitubercular AgentsFemaleHumansMaleRetention in CareRifampinTuberculosis, Multidrug-ResistantYoung AdultAntitubercular AgentsRifampinAfghanistandrug-resistant tuberculosisKandaharperson-centred careshort oral regimen

Identifiers

PMID34978748
PMCPMC9306566
OpenAlexW4205480990

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.