ArticleJournal of nephrology2022
Frailty in kidney transplant candidates: a comparison between physical frailty phenotype and FRAIL scales.
Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Understanding frailty across the kidney transplant continuum: a comprehensive systematic review of recent evidence.International urology and nephrology · 2026Pooled it
- A Snapshot View of Sarcopenia and Frailty Status in Kidney Transplant Recipients.Clinical transplantation · 2026Article
- Frailty assessment in kidney transplantation: insights from a European survey.Clinical kidney journal · 2026Article
- Comparison of diagnostic characteristics of four frailty screening tools in maintenance hemodialysis patients.International urology and nephrology · 2026Article
- Frailty in Focus: A Scoping Review of Frailty Instruments from the Kidney Disease Aging Research Collaborative.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Frailty Impact on Kidney Transplantation in Older People.Kidney international reports · 2025Article
- Renal transplantation in older adults: retrospective cohort study to examine the impact of the new 2019 kidney offering scheme on older adult transplant recipients.Annals of the Royal College of Surgeons of England · 2025Observational
- Frailty Assessment Tools in Chronic Kidney Disease: A Systematic Review and Meta-analysis.Kidney medicine · 2025Article
- Frailty Prevalence and Characterization Among Kidney Transplant Candidates in Spain: A Multicenter Study.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Frailty and solid-organ transplant candidates: a scoping review.BMC geriatrics · 2022Article
- Increased mortality after kidney transplantation in mildly frail recipients.Clinical kidney journal · 2022Article
- Frailty in the context of kidney transplantation.Jornal brasileiro de nefrologiaReview
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty is common among advanced chronic kidney disease (CKD) patients who are kidney transplant (KT) candidates, and predisposes to poor outcomes after transplantation. However, frailty is not routinely measured during pretransplant work-up and it is unknown which metric should be used in this specific population. Our aim was to establish frailty prevalence in KT candidates according to different frailty scales.
methodsProspective longitudinal study of 451 KT candidates evaluated for frailty by both Physical Frailty Phenotype (PFP) and FRAIL scale at the time of inclusion on the KT waiting list. Clinical and functional characteristics including sociodemographics, comorbidities, disability and nutritional status were recorded. Agreement between PFP and FRAIL scales as well as dissonant patients were analyzed.
resultsMean age was 60.9 years and 31.7% were female. Comorbidity burden among patients was high, with 36.9% and 16.2% presenting with diabetes and ischemic coronary disease, respectively. Disabilities were also frequent. More than 70% of patients presented with ≥ 1 PFP criteria while this percentage for ≥ 1 FRAIL criteria was 45.4%. Agreement between PFP and FRAIL was not good (kappa index 0.317). There were 132 patients who were pre-frail or frail according to PFP but non-frail according to the FRAIL scale and they presented with fewer comorbidities and less disability.
conclusionsFrailty is frequent in advanced CKD patients, although its prevalence may vary according to different scales. Agreement between PFP and FRAIL scale is not good, and FRAIL scale might misclassify as robust patients those frail/prefrail patients who are in better health conditions.
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