ArticleEuropean journal of nuclear medicine and molecular imaging2022
Cortical abnormalities of synaptic vesicle protein 2A in focal cortical dysplasia type II identified in vivo with
Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- EANM practice guidelines for an appropriate use of PET and SPECT for patients with epilepsy.European journal of nuclear medicine and molecular imaging · 2024Guideline
- Nuclear imaging for localization and surgical outcome prediction in epilepsy: A review of latest discoveries and future perspectives.Frontiers in neurology · 2022Pooled it
- Beyond FDG: a paradigm shift in precision localization of epileptogenic zones in refractory epilepsy using multimodal molecular imaging (PET/CT) and isotropic 3D MRI fusion.Journal of neurology · 2026Review
- Direct evidence for synaptic density changes in tinnitus:European journal of nuclear medicine and molecular imaging · 2026Article
- Seizure occurrence in FCD type II is predicted by lesion position and linked to cytoarchitectural alterations.Acta neuropathologica communications · 2025Article
- Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Multimodal quantitative analysis guides precise preoperative localization of epilepsy.Journal of neurology · 2025Review
- A comparative analysis of imaging-based algorithms for detecting focal cortical dysplasia type II in children.Scientific reports · 2025Article
- Characterization of in vivo binding kinetics and non-displaceable binding of [EJNMMI research · 2025Article
- Head-to-Head comparison of [European journal of nuclear medicine and molecular imaging · 2025Article
- Transcriptionally downregulated GABAergic genes associated with synaptic density network dysfunction in temporal lobe epilepsy.European journal of nuclear medicine and molecular imaging · 2025Article
- Presynaptic terminal integrity is associated with glucose metabolism in Parkinson's disease.European journal of nuclear medicine and molecular imaging · 2025Article
- Advances in synaptic PET imaging and intervention with synapse-targeted small-molecular drugs for dementia diagnosis and therapy.Fundamental research · 2025Review
- Loss of synaptic density in nucleus basalis of meynert indicates distinct neurodegeneration in Alzheimer's disease: the RJNB-D study.European journal of nuclear medicine and molecular imaging · 2024Observational
- GMP-compliant automated radiosynthesis of [EJNMMI radiopharmacy and chemistry · 2024Article
- [European journal of nuclear medicine and molecular imaging · 2024Article
- [European radiology · 2024Article
- Characteristics of ear fullness and synaptic loss in ear fullness revealed by SV2A positron emission tomographycortical.Frontiers in molecular neuroscience · 2024Article
- Predictive model for epileptogenic tubers from all tubers in patients with tuberous sclerosis complex based onBMC medicine · 2023Article
- In vivo synaptic density loss correlates with impaired functional and related structural connectivity in Alzheimer's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeThe loss of synaptic vesicle glycoprotein 2A (SV2A) is well established as the major correlate of epileptogenesis in focal cortical dysplasia type II (FCD II), but this has not been directly tested in vivo. In this positron emission tomography (PET) study with the new tracer
methodsSixteen patients with proven FCD II and 16 healthy controls were recruited. All FCD II patients underwent magnetic resonance imaging (MRI) and static PET imaging with both
resultsLesions in the brains of FCD II patients had significantly reduced
conclusionSV2A PET with
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.