Evidence map›Paper›PMID 34978547›Full record

ArticleMMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports2021

Dengue Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021.

Gabriela Paz-Bailey, Laura Adams, Joshua M Wong, Katherine A Poehling, Wilbur H Chen, Veronica McNally, Robert L Atmar, Stephen H Waterman

Open access · diamondAbstract read
In one paragraph

Article in MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.

  1. Vaccination of Adults With Cancer: ASCO Guideline.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Guideline
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Economic burden of dengue in Puerto Rico, 2010-2023.Infectious diseases of poverty · 2026
    Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Functional Roles and Host Interactions ofPathogens (Basel, Switzerland) · 2025
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Recommendations for dengue vaccine implementation in the elderly population.Therapeutic advances in vaccines and immunotherapy · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Gabriela Paz-Bailey
Laura Adams
Joshua M Wong
Katherine A Poehling
Wilbur H Chen
Veronica McNally
Robert L Atmar
Stephen H Waterman
National Center for Emerging and Zoonotic Infectious Diseases · USBaylor College of Medicine · USMichigan State University · USUniversity of Maryland, Baltimore · USWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue is a vectorborne infectious disease caused by dengue viruses (DENVs), which are predominantly transmitted by Aedes aegypti and Aedes albopictus mosquitos. Dengue is caused by four closely related viruses (DENV-1-4), and a person can be infected with each serotype for a total of four infections during their lifetime. Areas where dengue is endemic in the United States and its territories and freely associated states include Puerto Rico, American Samoa, the U.S. Virgin Islands, the Federated States of Micronesia, the Republic of Marshall Islands, and the Republic of Palau. This report summarizes the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of the Dengvaxia vaccine in the United States. The vaccine is a live-attenuated, chimeric tetravalent dengue vaccine built on a yellow fever 17D backbone. Dengvaxia is safe and effective in reducing dengue-related hospitalizations and severe dengue among persons who have had dengue infection in the past. Previous natural infection is important because Dengvaxia is associated with an increased risk for severe dengue in those who experience their first natural infection (i.e., primary infection) after vaccination. Dengvaxia was licensed by the Food and Drug Administration for use among children and adolescents aged 9-16 years (referred to in this report as children). ACIP recommends vaccination with Dengvaxia for children aged 9-16 having evidence of a previous dengue infection and living in areas where dengue is endemic. Evidence of previous dengue infection, such as detection of anti-DENV immunoglobulin G with a highly specific serodiagnostic test, will be required for eligible children before vaccination.

Indexed as

Dengue VaccinesYellow FeverAdolescentAdvisory CommitteesAnimalsChildHumansImmunizationUnited StatesVaccinationDengue Vaccines

Identifiers

PMID34978547
PMCPMC8694708
OpenAlexW4200261130

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.