ArticleInternational journal of STD & AIDS2022
Clinical features associated with neurosyphilis in people living with HIV and late latent syphilis.
Article in International journal of STD & AIDS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 11 citations in OpenAlex.
- A distinct IgM immunoblot signature differentiates neurosyphilis from latent syphilis.Microbiology spectrum · 2026Article
- CARE-NS, a research strategy for neurosyphilis.Frontiers in medicine · 2022Article
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Authors and funding
13 authors at 2 institutions in 1 country.
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Abstract
backgroundThe diagnosis of neurosyphilis is a challenge, and the criteria for deciding when to perform a lumbar puncture are still controversial, especially in people living with HIV with a late latent syphilis diagnosis.
methodsRetrospective analysis of demographic, clinical, and laboratory data of people with HIV and documented late latent syphilis or syphilis of unknown duration with a cerebrospinal fluid VDRL test.
results122 patients were evaluated, of whom 52 had the diagnosis of neurosyphilis. Patients with and without neurosyphilis presented a similar viral load and lymphocyte CD4
conclusionNeurological symptoms, particularly headache, were predictors of neurosyphilis in people with HIV irrespective of their viral load and lymphocyte CD4
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