Evidence map›Paper›PMID 34978027›Full record

ArticlePurinergic signalling2022

Selectivity of the P2X3 receptor antagonist Eliapixant, and its potential use in the treatment of endometriosis.

Michelle C Fletcher

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Purinergic signalling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04562155 (Randomized, Double-blind, Parallel Group, Phase 2b Dose-finding, Efficacy and Safety Study of 12-week Twice Daily Oral Administration of BAY 1817080 Compared to Placebo in the Treatment of Refractory and/or Unexplained Chronic Cough), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04562155 phase2completednot on this map

Randomized, Double-blind, Parallel Group, Phase 2b Dose-finding, Efficacy and Safety Study of 12-week Twice Daily Oral Administration of BAY 1817080 Compared to Placebo in the Treatment of Refractory and/or Unexplained Chronic Cough (RUCC)

TypeinterventionalSponsorBayerRan2020 to 2021Enrolled310ConditionsRefractory and/or Unexplained Chronic CoughArmsBAY1817080, Placebo
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Opiranserin (VVZ-149): what's new in analgesics.The Korean journal of pain · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michelle C FletcherBiomedical Research Centre, School of Biological Sciences, University of East Anglia, Norwich, UK. michelle.fletcher@uea.ac.uk.ORCID 0000-0002-1283-0963
University of East Anglia · GB

Funding

Biotechnology and Biological Sciences Research Council
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EndometriosisPurinergic P2X Receptor AntagonistsAdenosine TriphosphateFemaleHumansReceptors, Purinergic P2X3Adenosine TriphosphatePurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X3

Identifiers

PMID34978027
PMCPMC8850518
OpenAlexW4206745215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.