Evidence map›Paper›PMID 34977957›Full record

Trial reportAIDS and behavior2022

Stay-at-Home: The Impact of the COVID-19 Lockdown on Household Functioning and ART Adherence for People Living with HIV in Three Sub-districts of Cape Town, South Africa.

Linda S Campbell, Caroline Masquillier, Lucia Knight, Anton Delport, Neo Sematlane, Lorraine Tanyaradzwa Dube, Edwin Wouters

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  7. Observational
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  10. "Journal of ageing and longevity · 2025
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  20. The effect of the SARS-CoV2 pandemic and lockdown on non-Covid ICU admissions: Experience from a South African tertiary hospital.The Southern African journal of critical care : the official journal of the Critical Care Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Linda S CampbellCentre for Population, Family and Health, University of Antwerp, Prinsstraat 13, 2000, Antwerpen, Belgium. linda.campbell@uantwerpen.be.ORCID http://orcid.org/0000-0003-3391-4370
Caroline MasquillierCentre for Population, Family and Health, University of Antwerp, Prinsstraat 13, 2000, Antwerpen, Belgium.
Lucia KnightDivision of Social and Behavioural Sciences, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Anton DelportSchool of Public Health, Community and Health Sciences, University of the Western Cape, Cape Town, South Africa.
Neo SematlaneCentre for Population, Family and Health, University of Antwerp, Prinsstraat 13, 2000, Antwerpen, Belgium.
Lorraine Tanyaradzwa DubeSchool of Public Health, Community and Health Sciences, University of the Western Cape, Cape Town, South Africa.
Edwin WoutersCentre for Population, Family and Health, University of Antwerp, Prinsstraat 13, 2000, Antwerpen, Belgium.
University of Antwerp · BEUniversity of the Western Cape · ZAUniversity of Cape Town · ZA

Funding

The National Research Foundation, South Africa 116356VLIR-UOS Research Foundation ZA2018TEA474A102
6 · The paper itself

Abstract

In March 2020, the South African government imposed a lockdown to control COVID-19 transmission. Lockdown may affect people living with HIV's (PLWH) antiretroviral therapy (ART) adherence. Data from a cluster randomised control trial was collected from 152 PLWH in Cape Town sub-districts from October 2019-March 2020 when the lockdown halted collection. Subsequently, 83 PLWH were followed-up in June-July 2020. Random effects models were used to analyse: (1) changes between baseline and follow-up and (2) correlates of adherence during lockdown. At follow-up, there was an increase in the odds of being below the poverty line and the odds of experiencing violence decreased. Measures for well-being, household functioning, stigma and HIV competency improved. Violence, depression, food insecurity, and stigma were associated with poorer ART adherence; higher well-being scores were associated with better adherence. During lockdown, governments need to ensure financial support, access to (mental) health services, and services for those experiencing violence.Clinical Trial Number: Pan African Clinical Trial Registry, PACTR201906476052236. Registered on 24 June 2019.

Indexed as

COVID-19HIV InfectionsAnti-Retroviral AgentsCommunicable Disease ControlHumansMedication AdherenceSouth AfricaAnti-Retroviral AgentsAdherenceARTCOVID-19HIVLockdown

Identifiers

PMID34977957
PMCPMC8720535
OpenAlexW4206401267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.