Evidence map›Paper›PMID 34977940›Full record

ArticleMilitary medicine2022

Latent Class Patterns of Adverse Childhood Experiences and Their Relationship to Veteran Status and Sex in the National Epidemiologic Survey of Alcohol and Related Conditions Wave III.

Mara Tynan, Jennalee S Wooldridge, Fernanda Rossi, Caitlin L McLean, Marianna Gasperi, Jeane Bosch, Christine Timko, Matthew Herbert, Niloofar Afari

Open access · hybridAbstract read
In one paragraph

Article in Military medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Patterns of adverse childhood experiences and cardiovascular risk factors in U.S. adults.Stress and health : journal of the International Society for the Investigation of Stress · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mara TynanSan Diego Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California, San Diego, CA 92120, USA.
Jennalee S WooldridgeVA San Diego Healthcare System, San Diego, CA 92161, USA.
Fernanda RossiCenter for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park, CA 94025, USA.
Caitlin L McLeanVA San Diego Healthcare System, San Diego, CA 92161, USA.
Marianna GasperiVA San Diego Healthcare System, San Diego, CA 92161, USA.
Jeane BoschNational Center for PTSD, Dissemination & Training Division, VA Palo Alto Health Care System, Menlo Park, CA 94025, USA.
Christine TimkoCenter for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park, CA 94025, USA.
Matthew HerbertVA San Diego Healthcare System, San Diego, CA 92161, USA.
Niloofar AfariVA San Diego Healthcare System, San Diego, CA 92161, USA.ORCID 0000-0002-6489-378X
University of California San Diego · USVA Palo Alto Health Care System · USSan Diego State University · US

Funding

An ACT-enhanced Weight Management and Fitness Program for Navy PersonnelR01DK106415 · NIDDK · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI AFARI, NILOOFAR · 2016 to 2020
$2.5M
Chronic pain conditions and internalizing psychopathology, a genetic epidemiology investigation.IK2CX002107 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Marianna Gasperi · 2021 to 2026
–
Mindful Action for Pain: An Integrated Approach to Improve Chronic Pain FunctionIK2RX002807 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI HERBERT, MATTHEW · 2019 to 2023
–
CSRD VA IK2 CX002107NIDDK NIH HHS R01 DK106415RRD VA IK2 RX002807
6 · The paper itself

Abstract

introductionAdverse childhood experiences (ACEs) are associated with poor psychosocial and health outcomes in adulthood. Veterans and females experience ACEs disproportionately. A greater understanding of this disparity may be achieved by examining the relationship between distinct ACE patterns and these demographic characteristics. Therefore, this study examined distinct ACE patterns and their association with Veteran status, sex, and other demographics in a nationally representative sample of U.S. adults to inform interventions tailored to ACE patterns experienced by specific groups. MATERIALS AND

methodsLatent class analysis (LCA) was conducted with data from the National Epidemiologic Survey of Alcohol and Related Conditions-III, a nationally representative structured diagnostic interview conducted from 2012-2013. The target population was the noninstitutionalized adult population living in the USA. The analytic sample was 36,190 (mean age 46.5 years; 48.1% male). Of these participants, 3,111 were Veterans. Data were analyzed between September 2020 and January 2021.

resultsLatent class analysis revealed a four-class solution: (1) "Low adversity" (75.3%); (2) "Primarily household dysfunction" (9.0%); (3) "Primarily maltreatment" (10.7%); and (4) "Multiple adversity types" (5.1%). Compared to "Low adversity," members in the other classes were more likely to be Veterans (odds ratio (OR)C2vC1 = 1.33, ORC3vC1 = 1.55, ORC4vC1 = 1.98) and female (ORC2vC1 = 1.58, ORC3vC1 = 1.22, ORC4vC1 = 1.65). While lower education and income were also related to higher adversity class membership, Veteran status and sex were the strongest predictors, even when controlling for education and income.

conclusionsDistinct and meaningful patterns of ACEs identified in this study highlight the need for routine ACE screenings in Veterans and females. As in the current study, operationalizing and clustering ACEs can inform screening measures and trauma-informed interventions in line with personalized medicine. Future work can test if classes are differentially associated with health outcomes.

Indexed as

Adverse Childhood ExperiencesVeteransAdultFamily CharacteristicsFemaleHumansIncomeMaleMiddle AgedUnited States

Identifiers

PMID34977940
PMCPMC8963153
OpenAlexW4206442540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.