Evidence map›Paper›PMID 34977850›Full record

ArticleCell reports methods2021

Distinct classes of potassium channels fused to GPCRs as electrical signaling biosensors.

M Dolores García-Fernández, Franck C Chatelain, Hugues Nury, Anna Moroni, Christophe J Moreau

Open access · goldAbstract read
In one paragraph

Article in Cell reports methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Modular architecture of KEMBO reports · 2025
    Review
  2. Machine learning and protein allostery.Trends in biochemical sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

M Dolores García-FernándezUniversité Grenoble Alpes, CNRS, CEA, IBS, 71, av. Martyrs, CS10090, 38044 Grenoble Cedex9, France.
Franck C ChatelainUniversité Côte d'Azur, IPMC CNRS UMR7275, Laboratory of Excellence ICST, 660 route des Lucioles, 06650 Valbonne, France.
Hugues NuryUniversité Grenoble Alpes, CNRS, CEA, IBS, 71, av. Martyrs, CS10090, 38044 Grenoble Cedex9, France.
Anna MoroniUniversity of Milan, Department of Biosciences, Via Celoria 26, 20133 Milano, Italy.
Christophe J MoreauUniversité Grenoble Alpes, CNRS, CEA, IBS, 71, av. Martyrs, CS10090, 38044 Grenoble Cedex9, France.
Centre National de la Recherche Scientifique · FRUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ligand-gated ion channels (LGICs) are natural biosensors generating electrical signals in response to the binding of specific ligands. Creating

Indexed as

Biosensing TechniquesLigand-Gated Ion ChannelsAnimalsLigandsMiceReceptors, G-Protein-CoupledSignal TransductionLigand-Gated Ion ChannelsLigandsReceptors, G-Protein-Coupledallosteric regulationbiosensorselectrical signalG protein-coupled receptorsion channelsK2P channelsman-made ligand-gated ion channelsprotein engineeringviral channels

Identifiers

PMID34977850
PMCPMC8688152
OpenAlexW3216380300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.