Evidence map›Paper›PMID 34977637›Full record

ArticleArthroscopy, sports medicine, and rehabilitation2021

Patients Aged 50 Years and Older Have Greater Complication Rates After Anterior Cruciate Ligament Reconstruction: A Large Database Study.

Madeleine A Salesky, Jake F Oeding, Alan L Zhang, C Benjamin Ma, Brian T Feeley, Drew A Lansdown

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arthroscopy, sports medicine, and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07387939 (Anterior Cruciate Ligament Reconstruction in Patients Aged 50 Years and Older), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07387939 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Anterior Cruciate Ligament Reconstruction in Patients Aged 50 Years and Older

TypeobservationalSponsorI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioRan2024 to 2026Enrolled56ConditionsACL Injury
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Age-related changes in the quadriceps tendon: Collagen fibril diameter decreases with aging.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Quadriceps autograft is a viable graft choice for arthroscopic ACL reconstruction in patients over 50 years of age.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Article
  14. Article
  15. Article
  16. Anterior cruciate ligament tear increases the risk of venous thromboembolism: a population-based cohort study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Madeleine A SaleskySchool of Medicine.
Jake F OedingDepartment of Orthopaedic Surgery, University of California San Francisco, San Francisco, California, U.S.A.
Alan L ZhangDepartment of Orthopaedic Surgery, University of California San Francisco, San Francisco, California, U.S.A.
C Benjamin MaDepartment of Orthopaedic Surgery, University of California San Francisco, San Francisco, California, U.S.A.
Brian T FeeleyDepartment of Orthopaedic Surgery, University of California San Francisco, San Francisco, California, U.S.A.
Drew A LansdownDepartment of Orthopaedic Surgery, University of California San Francisco, San Francisco, California, U.S.A.
University of California, San Francisco · USIndiana University School of Medicine

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the use of anterior cruciate ligament (ACL) reconstruction in older adults and to compare postoperative complication and revision surgery rates between patients older than and younger than 50 years old.

methodsRetrospective data were obtained using the PearlDiver database for patients who underwent arthroscopic ACL reconstruction from January 2010 to December 2017. Trends in the annual performance of ACL reconstruction were determined using nonparametric test of trends of ranks. Patients in each age group were matched based on sex and the Charlson Comorbidity Index. The incidence of postoperative complications within 90 days and subsequent knee surgery within 2 years of ACL reconstruction was collected. Postoperative complication rates were compared between matched age groups using the χ

resultsA total of 20,993 patients aged 50 years and older and 154,817 patients younger than 50 years underwent ACL reconstruction between 2010 and 2017. The use of ACL reconstruction in patients aged 50 years or older decreased over time (

conclusionsACL reconstruction in patients aged 50 years or older is associated with greater complication rates but lower rates of subsequent knee surgery relative to patients younger than 50 years of age. Younger patients were more prone to surgical complications whereas older patients experienced more medical complications. The increased incidence of VTE in this population suggests that thrombotic prophylaxis may be considered. LEVEL OF EVIDENCE: Level III, retrospective comparative observational trial.

Identifiers

PMID34977637
PMCPMC8689249
OpenAlexW3205691023

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.