Evidence map›Paper›PMID 34977618›Full record

ArticleArthroscopy, sports medicine, and rehabilitation2021

Trochanteric Bursa Is a Source of Connective Tissue Progenitor Cells.

Matthew R LeVasseur, Benjamin C Hawthorne, Michael R Mancini, Mary Beth R McCarthy, Ian J Wellington, Mark P Cote, Olga Solovyova, Vincent J Williams, Augustus D Mazzocca

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arthroscopy, sports medicine, and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Matthew R LeVasseurDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, U.S.A.
Benjamin C HawthorneDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, U.S.A.
Michael R ManciniDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, U.S.A.
Mary Beth R McCarthyDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, U.S.A.
Ian J WellingtonDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, U.S.A.
Mark P CoteDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, U.S.A.
Olga SolovyovaDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, U.S.A.
Vincent J WilliamsDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, U.S.A.
Augustus D MazzoccaDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, Connecticut, U.S.A.
University of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the presence of connective tissue progenitor cells (CTPs) in the trochanteric bursa harvested over the gluteus medius muscle belly and tendon during open hip procedures.

methodsTrochanteric bursa samples from nine patients (63.1 ± 8.6 years) undergoing total hip arthroplasty for primary osteoarthritis were obtained from 2 sites: over the gluteus medius tendon at the greater trochanter and over the muscle belly. Bursal tissue was digested with collagenase and grown in culture. The nucleated cell count, cellular concentration, cellular proliferation, fluorescence-activated cell sorting (FACS) analysis, and differentiation using immunostaining and quantitative polymerase chain reaction (PCR) were used to determine and quantify the presence of CTPs.

resultsBursa-derived CTPs were identified in all harvested samples. At

conclusionsConnective tissue progenitor cells are found in the trochanteric bursa overlying the muscle and tendon of the hip abductors. CLINICAL RELEVANCE: During open hip procedures, the trochanteric bursa is often partially excised to identify muscular boundaries and tissue planes for surgical exposure. The function of the trochanteric bursa remains largely unknown. However, this tissue is a source of connective tissue progenitor cells, which may be important in the healing response of surgically repaired abductor tendons.

Identifiers

PMID34977618
PMCPMC8689227
OpenAlexW3197096381

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.