ArticleiScience2022
Remote cortical perturbation dynamically changes the network solutions to given tactile inputs in neocortical neurons.
Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- D-amphetamine alters the dynamic ECoG activity distribution patterns in the rat neocortex.Scientific reports · 2025Article
- High-dimensional cortical signals reveal rich bimodal and working memory-like representations among S1 neuron populations.Communications biology · 2024Article
- Local field potential sharp waves with diversified impact on cortical neuronal encoding of haptic input.Scientific reports · 2024Article
- ECoG activity distribution patterns detects global cortical responses following weak tactile inputs.iScience · 2024Article
- Hippocampal output profoundly impacts the interpretation of tactile input patterns in SI cortical neurons.iScience · 2023Article
- Differential encoding of temporally evolving color patterns across nearby V1 neurons.Frontiers in cellular neuroscience · 2023Article
- Remembrance of things perceived: Adding thalamocortical function to artificial neural networks.Frontiers in integrative neuroscience · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neocortex has a globally encompassing network structure, which for each given input constrains the possible combinations of neuronal activations across it. Hence, its network contains solutions. But in addition, the cortex has an ever-changing multidimensional internal state, causing each given input to result in a wide range of specific neuronal activations. Here we use intracellular recordings in somatosensory cortex (SI) neurons of anesthetized rats to show that remote, subthreshold intracortical electrical perturbation can impact such constraints on the responses to a set of spatiotemporal tactile input patterns. Whereas each given input pattern normally induces a wide set of preferred response states, when combined with cortical perturbation response states that did not otherwise occur were induced and consequently made other response states less likely. The findings indicate that the physiological network structure can dynamically change as the state of any given cortical region changes, thereby enabling a rich, multifactorial, perceptual capability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.