Evidence map›Paper›PMID 34977483›Full record

ReviewAnimal models and experimental medicine2021

The hypoxia adaptation of small mammals to plateau and underground burrow conditions.

Mengke Li, Dan Pan, Hong Sun, Lei Zhang, Han Cheng, Tian Shao, Zhenlong Wang

Open access · diamondAbstract readReview
In one paragraph

Review in Animal models and experimental medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Hypoxic and hypercapnic burrow conditions lead to downregulation of free triiodothyronine and hematocrit in Ansell's mole-rats (Fukomys anselli).Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Article
  10. Exceptional Survival of a Buried Alive Newborn: A Case Report.International medical case reports journal · 2024
    Article
  11. Article
  12. Breathing patterns and CORespiratory physiology & neurobiology · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mengke LiSchool of Life Sciences Zhengzhou University Zhengzhou P.R. China.ORCID 0000-0002-7222-4420
Dan PanSchool of Life Sciences Zhengzhou University Zhengzhou P.R. China.
Hong SunSchool of Life Sciences Zhengzhou University Zhengzhou P.R. China.
Lei ZhangSchool of Life Sciences Zhengzhou University Zhengzhou P.R. China.
Han ChengSchool of Life Sciences Zhengzhou University Zhengzhou P.R. China.
Tian ShaoSchool of Life Sciences Zhengzhou University Zhengzhou P.R. China.
Zhenlong WangSchool of Life Sciences Zhengzhou University Zhengzhou P.R. China.ORCID 0000-0001-5946-2806
Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen is one of the important substances for the survival of most life systems on the earth, and plateau and underground burrow systems are two typical hypoxic environments. Small mammals living in hypoxic environments have evolved different adaptation strategies, which include increased oxygen delivery, metabolic regulation of physiological responses and other physiological responses that change tissue oxygen utilization. Multi-omics predictions have also shown that these animals have evolved different adaptations to extreme environments. In particular, vascular endothelial growth factor (VEGF) and erythropoietin (EPO), which have specific functions in the control of O

Indexed as

Adaptation, PhysiologicalAnaerobiosisMole RatsAnimalsVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Ahypoxia adaptationmulti‐omicsplateausmall mammalsunderground burrow systems

Identifiers

PMID34977483
PMCPMC8690988
OpenAlexW3209790000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.