ArticleVeterinary and animal science2021
Impact of general anesthesia on rotational thromboelastometry (ROTEM) parameters and standard plasmatic coagulation tests in healthy Beagle dogs.
Article in Veterinary and animal science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Comparison of viscoelastic coagulation parameters, blood loss and surgical time between asymptomatic heartworm antigen-positive and negative dogs presented for elective gonadectomy.The Journal of small animal practice · 2025Article
- Evaluation of the Effect of Induced Endotoxemia on ROTEM SAnimals : an open access journal from MDPI · 2023Article
- Evaluation of Haemostasis in Dogs Affected by Resectable Malignancy.Animals : an open access journal from MDPI · 2022Article
- Point-of-care viscoelastic coagulation assessment in healthy dogs during the perianesthetic period.BMC veterinary research · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the influence of general anesthesia on rotational thromboelastometry (ROTEM) and standard coagulation testing in healthy dogs. STUDY
designProspective experimental study. ANIMALS: 10 healthy Beagle dogs.
methodsDogs were administered methadone (0.2 mg/kg) intramuscularly. Anesthesia was co-induced intravenously 30 min later with midazolam (0.1 mg/kg) and propofol to effect, and maintained with sevoflurane. Crystalloids were administered at 5 ml/kg/h. Blood was sampled by direct venipuncture before induction (T0) and 3.5 h later (T3.5) and ROTEM parameters (ExTEM, InTEM, FibTEM, ApTEM), standard plasmatic coagulation tests (prothrombin time [PT], activated partial thromboplastin time [aPTT], fibrinogen concentration), hematology, ionized calcium, triglycerides, pH, lactate and body temperature were compared over time with Students t - test or Wilcoxon matched pairs signed-rank tests.
resultsThe following variables dropped significantly between T0 and T3.5: body temperature ( CONCLUSION AND CLINICAL RELEVANCE: General anesthesia with concurrent hemodilution and hypothermia induced significant but clinically irrelevant changes in coagulation variables measured at 37 °Celsius. Blood samples from anaesthetized animals can be used for determination of coagulation status in dogs.
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