ReviewHeliyon2021
Longevity, cellular senescence and the gut microbiome: lessons to be learned from crocodiles.
Review in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Gut microbiome, stress and interventional strategies using hardy animals.Future science OA · 2025Review
- Age and anatomical site shape the gastrointestinal bacterial communities of captive American crocodiles (Crocodylus acutus).Folia microbiologica · 2025Article
- Multi-Omics Analysis of Gut Microbiome and Host Metabolism in Different Populations of Chinese Alligators (Ecology and evolution · 2025Article
- Recent advances in crocodilian oil research: bioactive components and potential therapeutic applications.Frontiers in medicine · 2025Review
- The Potential of Naturally Derived Compounds for Treating Chronic Kidney Disease: A Review of Autophagy and Cellular Senescence.International journal of molecular sciences · 2024Review
- Gut microbiome of Crocodylus porosus and cellular stress: inhibition of nitric oxide, interleukin 1-beta, tumor necrosis factor-alpha, and prostaglandin E2 in cerebrovascular endothelial cells.Archives of microbiology · 2023Article
- Space medicine: gut microbiome of hardy species is a potential source to counter disorders during space travel.Future science OA · 2023Article
- Microbiome and One Health: Potential of Novel Metabolites from the Gut Microbiome of Unique Species for Human Health.Microorganisms · 2023Article
- Effect of Microgravity on the Gut Microbiota Bacterial Composition in a Hindlimb Unloading Model.Life (Basel, Switzerland) · 2022Article
- The Use of Gut Microbial Modulation Strategies as Interventional Strategies for Ageing.Microorganisms · 2022Review
- Novel Sources of Bioactive Molecules: Gut Microbiome of Species Routinely Exposed to Microorganisms.Veterinary sciences · 2022Review
- Improving the effectiveness of anti-aging modalities by using the constrained disorder principle-based management algorithms.Frontiers in aging · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crocodiles are flourishing large-bodied ectotherms in a world dominated by endotherms. They survived the Cretaceous extinction event, that eradicated the dinosaurs who are thought to be their ancestral hosts. Crocodiles reside in polluted environments; and often inhabit water which contains heavy metals; frequent exposure to radiation; feed on rotten meat and considered as one of the hardy species that has successfully survived on this planet for millions of years. Another capability that crocodiles possess is their longevity. Crocodiles live much longer than similar-sized land mammals, sometimes living up to 100 years. But how do they withstand such harsh conditions that are detrimental to
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.