Evidence map›Paper›PMID 34977378›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2022

Organic acid blends improve intestinal integrity, modulate short-chain fatty acids profiles and alter microbiota of broilers under necrotic enteritis challenge.

Alip Kumar, Mehdi Toghyani, Sarbast K Kheravii, Lane Pineda, Yanming Han, Robert A Swick, Shu-Biao Wu

Open access · goldAbstract read
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
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  17. Microorganisms · 2024
    Review
  18. Citric Acid Promotes Immune Function by Modulating the Intestinal Barrier.International journal of molecular sciences · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alip KumarSchool of Environmental and Rural Science, University of New England, Armidale, NSW, 2351, Australia.
Mehdi ToghyaniSchool of Environmental and Rural Science, University of New England, Armidale, NSW, 2351, Australia.
Sarbast K KheraviiSchool of Environmental and Rural Science, University of New England, Armidale, NSW, 2351, Australia.
Lane PinedaTrouw Nutrition R & D, Stationsstraat 77, 3811, MH, Amersfoort, the Netherlands.
Yanming HanTrouw Nutrition R & D, Stationsstraat 77, 3811, MH, Amersfoort, the Netherlands.
Robert A SwickSchool of Environmental and Rural Science, University of New England, Armidale, NSW, 2351, Australia.
Shu-Biao WuSchool of Environmental and Rural Science, University of New England, Armidale, NSW, 2351, Australia.
University of New England · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Controlling enteric diseases of broilers is crucial. Among many additives, organic acids (OA) and their blends are gaining attention to combat diseases in the post-antibiotic era. The current study evaluated the potentials of short-chain fatty acids (SCFA) and medium-chain fatty acids (MCFA) blends and/or phenolic compounds on intestinal integrity, intestinal pH, caecal microbiota, and caecal SCFA profiles of broilers under necrotic enteritis (NE) challenge. The additives used were: (A) a blend of SCFA, MCFA, and a phenolic compound (SMP), (B) a blend of free and buffered SCFA with MCFA (SMF), and (C) a blend of free and buffered SCFA with a high concentration of MCFA (SHM). A total of 1,404 male parental chicks of Ross 308 broilers were randomly allocated to 78 floor pens on hatching day with 6 treatments replicated 13 times with 18 birds per pen. The treatments were: UCC, unchallenged control; CHC, challenged control; BAC, challenged group plus zinc bacitracin; SMP, challenged group plus additive SMP; SMF, challenged group plus additive SMF; SHM, challenged group plus additive SHM. Birds were challenged with field-strain

Indexed as

Alternative to antibioticsBroiler chickenIntestinal healthNecrotic enteritisOrganic acid blend

Identifiers

PMID34977378
PMCPMC8669248
OpenAlexW3199157580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.